Document Detail

Single photon emission computed tomography in patients with acute hydrocephalus or with cerebral ischaemia after subarachnoid haemorrhage.
MedLine Citation:
PMID:  1880509     Owner:  NLM     Status:  MEDLINE    
Using single photon emission computed tomography (SPECT), cerebral blood flow was studied in eight patients with gradual deterioration in the level of consciousness after subarachnoid haemorrhage. Four had cerebral ischaemia and four had acute hydrocephalus. In patients with cerebral ischaemia, single photon emission computed tomography scanning showed multiple regions with decreased uptake of technetium-99M labelled d,l-hexamethyl-propylene amine oxime (99mTcHM-PAO) mainly in watershed areas. In patients with acute hydrocephalus, decreased uptake was seen mainly in the basal parts of the brain: around the third ventricle, around the temporal horns of the lateral ventricles, and in the basal part of the frontal lobe. After serial lumbar puncture, there was improvement of the uptake of 99mTc HM-PAO in these basal areas in three (convincingly in two and slightly in the other) of the four patients accompanied by clinical improvement in these three patients. These results suggest that patients with acute hydrocephalus and impaired consciousness after SAH, in contrast to patients with cerebral ischaemia, have decreased cerebral blood flow predominantly in the basal parts of the brain.
D Hasan; J van Peski; I Loeve; E P Krenning; M Vermeulen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of neurology, neurosurgery, and psychiatry     Volume:  54     ISSN:  0022-3050     ISO Abbreviation:  J. Neurol. Neurosurg. Psychiatr.     Publication Date:  1991 Jun 
Date Detail:
Created Date:  1991-10-01     Completed Date:  1991-10-01     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985191R     Medline TA:  J Neurol Neurosurg Psychiatry     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  490-3     Citation Subset:  IM    
Department of Neurology, University Hospital, Dijkzigt, Rotterdam, The Netherlands.
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MeSH Terms
Acute Disease
Brain Ischemia / radionuclide imaging*
Cerebrovascular Circulation / physiology
Follow-Up Studies
Hydrocephalus / radionuclide imaging*
Intracranial Aneurysm / radionuclide imaging
Organotechnetium Compounds / diagnostic use
Oximes / diagnostic use
Spinal Puncture
Subarachnoid Hemorrhage / radionuclide imaging*
Technetium Tc 99m Exametazime
Tomography, Emission-Computed, Single-Photon*
Tomography, X-Ray Computed
Reg. No./Substance:
0/Organotechnetium Compounds; 0/Oximes; 100504-35-6/Technetium Tc 99m Exametazime

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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