Document Detail


Single dose treatment of vaginal candidosis: comparison of clotrimazole and isoconazole.
MedLine Citation:
PMID:  6365236     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The therapeutic efficacy of a single dose 500 mg tablet of clotrimazole was compared with two 300 mg tablets of isoconazole in an open randomised study of 100 patients with vaginal candidosis confirmed by mycological culture. One week after treatment 100% of the clotrimazole treated patients and 98% of the isoconazole treated group gave mycologically negative results. Five weeks after treatment these figures were 74% and 78% respectively, showing that both regimens were equally effective.
Authors:
L Cohen
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  The British journal of venereal diseases     Volume:  60     ISSN:  0007-134X     ISO Abbreviation:  Br J Vener Dis     Publication Date:  1984 Feb 
Date Detail:
Created Date:  1984-03-30     Completed Date:  1984-03-30     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0421042     Medline TA:  Br J Vener Dis     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  42-4     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Candidiasis, Vulvovaginal / drug therapy*
Clinical Trials as Topic
Clotrimazole / administration & dosage*,  therapeutic use
Drug Administration Schedule
Female
Humans
Imidazoles / administration & dosage*
Miconazole / administration & dosage,  analogs & derivatives*,  therapeutic use
Time Factors
Chemical
Reg. No./Substance:
0/Imidazoles; 22916-47-8/Miconazole; 23593-75-1/Clotrimazole; 27523-40-6/isoconazole
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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