| Single-dose time-resolved contrast enhanced hybrid MR angiography in diagnosis of peripheral arterial disease: compared with digital subtraction angiography. | |
| | |
MedLine Citation:
|
PMID: 20882624 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: To prospectively study the diagnostic performance of hybrid single-dose contrast-enhanced MRA of peripheral arterial disease (PAD), with digital subtraction angiography (DSA) as the reference standard. MATERIALS AND METHODS: Hybrid MRA, combining time resolved imaging of contrast kinetics and two-station bolus-chase sequences, of lower limb was performed in 31 PAD patients (21 men, 10 women; mean age, 72 years) with two separate gadobenate dimeglumine (8 mL) injections in each sequence. Two independent blinded readers analyzed the vascular stenosis (32 segments in each limb). Sensitivity, specificity, and accuracy in all vascular segments and segments below popliteal artery were calculated. Interobserver agreements on MRA and intermodality agreements between MRA and DSA were calculated by using k statistics. RESULTS: Sensitivity, specificity, and accuracy of the hybrid MRA with regard to hemodynamically significant stenosis in all vascular segments were 92%, 97%, and 95% for reader 1, and 90%, 92%, and 92%, for reader 2, respectively. The interobsever agreements on MRA were good (k = 0.77-0.74) for all-grade stenosis, and excellent (k = 0.82-0.81) for hemadynamically significant stenosis. The intermodality agreements are good to excellent (k = 0.73-0.94). CONCLUSION: Single-dose hybrid MRA is a safe and reliable noninvasive alternative to conventional DSA in the assessment of PAD patients. |
| | |
Authors:
|
Chun-Chieh Wang; Huei-Lung Liang; Chia-Chi Hsiao; Matt Chiung-Yu Chen; To-Ho Wu; Chieh-Jen Wu; Jer-Shyung Huang; Yih-Huei Lin; Huay-Ben Pan |
Related Documents
:
|
9111674 - Mr angiography in acute cerebral ischemia of the anterior circulation: a preliminary re... 8641094 - Comparison of magnetic resonance angiography with conventional angiography in the detec... 16178014 - Cost-effectiveness of diagnostic strategies prior to carotid endarterectomy. 20350674 - Vertebral artery hypoplasia: prevalence and reliability of identifying and grading its ... 22347934 - Ct colonography: avoiding traps and pitfalls. 10934954 - Reproducibility in double scanning of cervical smears with the papnet system. |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Journal of magnetic resonance imaging : JMRI Volume: 32 ISSN: 1522-2586 ISO Abbreviation: J Magn Reson Imaging Publication Date: 2010 Oct |
Date Detail:
|
Created Date: 2010-09-30 Completed Date: 2011-02-02 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9105850 Medline TA: J Magn Reson Imaging Country: United States |
Other Details:
|
Languages: eng Pagination: 935-42 Citation Subset: IM |
Affiliation:
|
Department of Radiology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Aged, 80 and over Angiography, Digital Subtraction / methods* Constriction, Pathologic / pathology Female Fibrosis Humans Kinetics Magnetic Resonance Angiography / methods* Male Middle Aged Observer Variation Peripheral Arterial Disease / diagnosis*, pathology* Reference Standards Reproducibility of Results |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Toward local arterial input functions in dynamic contrast-enhanced MRI.
Next Document: Frequency response of multipoint chemical shift-based spectral decomposition.