| A single-centre report on the characteristics of Tako-tsubo syndrome. | |
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MedLine Citation:
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PMID: 19914869 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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BACKGROUND: Tako-tsubo cardiomyopathy is an increasingly recognised phenomenon characterised by chest pain, ECG abnormalities, cardiac biomarker elevation and transient left ventricular dysfunction without significant coronary artery obstruction. AIMS: To report the clinical and echocardiographic characteristics from a large single-centre Australian series of patients with Tako-tsubo syndrome. METHODS: We prospectively collected data on 23 consecutive patients presenting between November 2005 and November 2007. Baseline demographics, ECG, echocardiography and coronary angiography were performed on nearly all patients. RESULTS: All patients presented with chest pain; 87% were female. Various stressors were noted and cardiac Troponin-T was elevated in 91% of patients. All patients had non-obstructive coronary disease at angiography. 19/23 patients had initial and subsequent echocardiography. Mean ejection fraction was 50% at baseline and 64% at follow-up (p<0.0001). Right ventricular dysfunction was present in eight, dynamic left ventricular outflow tract obstruction in two, diastolic dysfunction in seven and two patients had the mid-cavity variant. CONCLUSIONS: This large prospective single-centre Australian series of Tako-tsubo syndrome is in concert with previous published series. Complete recovery of left ventricular function on echocardiographic follow-up was typical. Although its pathogenesis remains unclear, early distinction from acute coronary syndromes is important and the prognosis is reassuringly good. |
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Authors:
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Andrew W Teh; Gishel New; Jennifer Cooke |
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Publication Detail:
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Type: Journal Article Date: 2009-11-14 |
Journal Detail:
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Title: Heart, lung & circulation Volume: 19 ISSN: 1444-2892 ISO Abbreviation: Heart Lung Circ Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-02-04 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100963739 Medline TA: Heart Lung Circ Country: Australia |
Other Details:
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Languages: eng Pagination: 63-70 Citation Subset: IM |
Copyright Information:
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Crown Copyright (c) 2009. Published by Elsevier B.V. All rights reserved. |
Affiliation:
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Department of Cardiology Box Hill Hospital, Victoria 3128, Australia. teh_wrx@yahoo.com.au |
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| Comments/Corrections | |
Comment In:
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Heart Lung Circ. 2010 Feb;19(2):61-2
[PMID:
20129114
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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