Document Detail


Single-center experience of catheter ablation for atrial fibrillation using multi-electrode mapping and ablation catheters.
MedLine Citation:
PMID:  21972158     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
PURPOSE: Radiofrequency ablation (RFA) is an established therapy for the treatment of paroxysmal and persistent atrial fibrillation (AF). Many techniques have been reported to achieve RFA. We report a single-center experience of RFA using three multi-electrode catheters.
METHODS: We collected data of the patients who had RFA for AF using custom-designed multi-electrode mapping and ablation catheters between May 2007 and November 2009 at this center.
RESULTS: A total of 105 patients aged 56 ± 9.6 years underwent RFA using three multi-electrode catheters. Eighty-seven patients were new and 18 patients had re-do AF ablation using the multi-electrode mapping and ablation catheters. In the new patients, the mean procedure duration was 141 ± 38 minutes and fluoroscopy time was 38 ± 4 minutes. The mean duration of follow-up was 15.8 ± 6.4 months. Symptomatic improvement was achieved in 75 patients (86%), 48 patients (55%) remained in sinus rhythm (SR) after the first procedure, while 7 (8%) had multiple procedures and remained in SR without antiarrhythmic drugs (AAD). Fourteen patients (16%) required AAD following a single procedure and 1 patient (1.1%) after multiple procedures to remain in SR. Seven patients (8%) had reduced burden of symptoms. No improvement occurred in 12 patients (13.7%). In the 18 re-do patients, 15 (83.3%) had symptom improvement. Four patients (22.2%) remained in SR after a single procedure and 4 patients (22.2%) required multiple procedures to remain in SR without AAD. One patient (5.5%) remained in SR on AAD following a single procedure and 1 patient (5.5%) remained in SR on AAD following multiple procedures. Five patients (27%) had reduced burden of symptoms and 3 patients (16.6%) had no improvement.
CONCLUSION: PVI using multi-electrode mapping and ablation catheters is an effective treatment of paroxysmal and persistent AF with a complication rate equivalent to published data.
Authors:
Mehmood Zeb; Arthur Yue; Paul Andrew Scott; Paul R Roberts; John M Morgan
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of invasive cardiology     Volume:  23     ISSN:  1557-2501     ISO Abbreviation:  J Invasive Cardiol     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-10-05     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8917477     Medline TA:  J Invasive Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  407-13     Citation Subset:  IM    
Affiliation:
Wessex Cardiothoracic Unit, Department Cardiology, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD. mehmoodzeb@hotmail.com.
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