| Single breath tracing for carbon dioxide in septic patients with tissue hypoxia. | |
| | |
MedLine Citation:
|
PMID: 17727266 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We investigated whether tissue hypoxia in sepsis produces substantial modifications of convective airway washout and consequently of CO2 transit time. Single breath tracing for carbon dioxide (SBT-CO2) was analysed in 18 ICU septic patients. Nine patients had tissue hypoxia events. Using the Hill formula, all tracings were analysed point by point to obtain the time required for CO2 to achieve 50% maximal value and the Fractional Expiratory Time 50 (FET0.5). Hypoxic patients FET0.5 and CO2 clearance were compared with non-hypoxic patients data. In hypoxic group CvCO2, CO2 clearance and FET0.5 values were higher than in non hypoxic group. During the recovery from hypoxia capnographic parameters did not differ from those recorded in the hypoxic period. CO2 clearance, but not FET0.5, correlated with arterial lactate and base excess either in hypoxic or in recovery period. In conclusion in septic patients tissue hypoxia influences CO2 elimination, modifying SB-CO2 tracing and lengthening FET0.5. |
| | |
Authors:
|
Renzo Zatelli |
Related Documents
:
|
11055656 - Plasmapheresis as part of the treatment for septic shock. 8027896 - Proximal interphalangeal joint autofusions after extensive burns. 10431986 - Electric burns: high- and low-tension injuries. 16941756 - Etomidate, pharmacological adrenalectomy and the critically ill: a matter of vital imp... 9888096 - Visceral organ abscesses in melioidosis: sonographic findings. 1807526 - Posterior cervical fusion with triple-wire strut graft technique: one hundred consecuti... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Advances in experimental medicine and biology Volume: 599 ISSN: 0065-2598 ISO Abbreviation: Adv. Exp. Med. Biol. Publication Date: 2007 |
Date Detail:
|
Created Date: 2007-08-30 Completed Date: 2007-12-10 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0121103 Medline TA: Adv Exp Med Biol Country: United States |
Other Details:
|
Languages: eng Pagination: 207-12 Citation Subset: IM |
Affiliation:
|
Dept. of Anesthesia and Intensive Care, University of Ferrara, 44100 Ferrara, Italy. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Anoxia / metabolism* Capnography / methods* Carbon Dioxide / metabolism* Humans Middle Aged Sepsis / metabolism* |
| Chemical | |
Reg. No./Substance:
|
124-38-9/Carbon Dioxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Increased sensitivity to transient global ischemia in aging rat brain.
Next Document: Design of new plasmepsin inhibitors: a virtual high throughput screening approach on the EGEE grid.