Document Detail

Single-breath measurement of lung mechanics in very low birth weight infants.
MedLine Citation:
PMID:  3965247     Owner:  NLM     Status:  MEDLINE    
The expiratory time constant of the respiratory system (Trs) and the total respiratory system compliance (Crs) were measured from the analysis of a flow-volume loop during relaxed expiration, and the total respiratory system resistance (Rrs) was derived from the relationship: Rrs = Trs/Crs. In ten intubated and mechanically ventilated very low birth weight infants, the values obtained for compliance (0.21 to 0.71 ml/cm H2O) were similar to those found using an occlusion technique during spontaneous breathing. The values of Trs were 0.03 to 0.14 sec. These Trs values were altered by adding known resistive loads. The corresponding derived values for Rrs were close to the values of the added resistance loads, suggesting that resistance values found in this group of ventilated babies (120 to 380 cm H2O/L X sec) were accurate.
A Thomson; M Silverman
Related Documents :
16223387 - Hemodynamic effects of spontaneous breathing in the post-operative period.
12373467 - Effects of spontaneous breathing during airway pressure release ventilation on renal pe...
3202377 - Effect of transdiaphragmatic pressure partitioning on activation and fatigue of the dia...
18974367 - The physiology and pathophysiology of human breath-hold diving.
12423277 - Rabbit model of non-cirrhotic portal fibrosis with repeated immunosensitization by rabb...
23613447 - Acute changes in blood pressure in patients with neuroblastoma treated with ¹³¹i-met...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Critical care medicine     Volume:  13     ISSN:  0090-3493     ISO Abbreviation:  Crit. Care Med.     Publication Date:  1985 Jan 
Date Detail:
Created Date:  1985-02-11     Completed Date:  1985-02-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0355501     Medline TA:  Crit Care Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  4-8     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Infant, Low Birth Weight*
Infant, Newborn
Intubation, Intratracheal
Plethysmography, Whole Body
Respiration, Artificial
Respiratory Distress Syndrome, Newborn / physiopathology*,  therapy
Respiratory Insufficiency / physiopathology*,  therapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Efficacy and safety of naloxone in septic shock.
Next Document:  ICU physician's ethical role in distributing scarce resources.