Document Detail

Single-breath measurement of lung mechanics in very low birth weight infants.
MedLine Citation:
PMID:  3965247     Owner:  NLM     Status:  MEDLINE    
The expiratory time constant of the respiratory system (Trs) and the total respiratory system compliance (Crs) were measured from the analysis of a flow-volume loop during relaxed expiration, and the total respiratory system resistance (Rrs) was derived from the relationship: Rrs = Trs/Crs. In ten intubated and mechanically ventilated very low birth weight infants, the values obtained for compliance (0.21 to 0.71 ml/cm H2O) were similar to those found using an occlusion technique during spontaneous breathing. The values of Trs were 0.03 to 0.14 sec. These Trs values were altered by adding known resistive loads. The corresponding derived values for Rrs were close to the values of the added resistance loads, suggesting that resistance values found in this group of ventilated babies (120 to 380 cm H2O/L X sec) were accurate.
A Thomson; M Silverman
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Critical care medicine     Volume:  13     ISSN:  0090-3493     ISO Abbreviation:  Crit. Care Med.     Publication Date:  1985 Jan 
Date Detail:
Created Date:  1985-02-11     Completed Date:  1985-02-11     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0355501     Medline TA:  Crit Care Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  4-8     Citation Subset:  AIM; IM    
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MeSH Terms
Infant, Low Birth Weight*
Infant, Newborn
Intubation, Intratracheal
Plethysmography, Whole Body
Respiration, Artificial
Respiratory Distress Syndrome, Newborn / physiopathology*,  therapy
Respiratory Insufficiency / physiopathology*,  therapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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