| Single-blind, prospective, randomized study of cefmetazole and cefoxitin in the treatment of postcesarean endometritis. | |
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MedLine Citation:
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PMID: 18475417 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The purpose of this study was to compare the clinical efficacy and safety of cefmetazole given by IV push with that of parenterally administered cefoxitin for the treatment of endometritis following cesarean delivery. METHODS: In a single-blind, multicenter, prospective, randomized study, 355 patients with endometritis after cesarean delivery were enrolled and received medication. Administered was either cefmetazole sodium, 2 g by IV push over 1 min q 8 h, or cefoxitin sodium, 2 g IV q 6 h in a 2:1 ratio. The patients were followed for clinical responses and side effects. RESULTS: The cure rate for cefmetazole was 89% and for cefoxitin it was 79% (P = 0.006). The adverse events were similar in both groups. CONCLUSIONS: Cefmetazole was significantly more effective than cefoxitin in the treatment of endometritis following cesarean delivery. |
Authors:
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A Chatwani; M Martens; D A Grimes; M Chatterjee; M Noah; M M Stamp-Cole; K T Perry; |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Infectious diseases in obstetrics and gynecology Volume: 3 ISSN: 1064-7449 ISO Abbreviation: Infect Dis Obstet Gynecol Publication Date: 1995 |
Date Detail:
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Created Date: 2008-05-13 Completed Date: 2010-06-30 Revised Date: 2010-09-14 |
Medline Journal Info:
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Nlm Unique ID: 9318481 Medline TA: Infect Dis Obstet Gynecol Country: Egypt |
Other Details:
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Languages: eng Pagination: 28-33 Citation Subset: - |
Affiliation:
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Department of Ob/Gyn/REI Temple University Hospital 3401 N. Broad Street, Philadelphia, PA 19140, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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Journal Information Journal ID (nlm-ta): Infect Dis Obstet Gynecol ISSN: 1064-7449 ISSN: 1098-0997 Publisher: Hindawi Publishing Corporation |
Article Information Download PDF  Copyright ? 1995 Hindawi Publishing Corporation. open-access: This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Received Day: 28 Month: 9 Year: 1994 Accepted Day: 14 Month: 2 Year: 1995 Print publication date: Year: 1995 Volume: 3 Issue: 1 First Page: 28 Last Page: 33 ID: 2364413 PubMed Id: 18475417 Publisher Item Identifier: S1064744995000263 DOI: 10.1155/S1064744995000263 |
| Single-Blind, Prospective, Randomized Study of Cefmetazole and Cefoxitin in the Treatment of Postcesarean Endometritis | |
| Ashwin Chatwani1 | |
| Mark Martens2 | |
| David A. Grimes3 | |
| Molly Chatterjee4 | |
| Melvin Noah5 | |
| Marion M. Stamp-Cole5 | |
| Kimberly T. Perry5 | |
| the Cefmetazole Study Group | |
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1Department of Ob/Gyn/REITemple University Hospital3401 N. Broad StreetPhiladelphiaPA19140USA |
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2University of Texas Medical Branch at GalvestonTXUSA |
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3University of CaliforniaSan Francisco General HospitalSan FranciscoCAUSA |
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4University of New Mexico School of MedicineAlbuquerqueNMUSA |
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5Upjohn CompanyKalamazooMIUSA |
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