| Single-acquisition dual-energy multidetector computed tomography: analysis of vascular enhancement and postprocessing techniques for evaluating the thoracic aorta. | |
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MedLine Citation:
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PMID: 20861768 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: The objectives of this study were (1) to evaluate the potential of low-peak kilovoltage (kVp) images acquired with dual-energy computed tomography (DECT) to improve aortic attenuation and reduce contrast agent utilization and (2) to evaluate the feasibility of material-specific DECT imaging for evaluating aortic disease. MATERIALS AND METHODS: Aortic imaging characteristics of 2 groups of patients examined with DECT were compared. In the first group, CT angiography (CTA) was performed in patients with known or suspected aortic disease (CTA group: n = 20, 100-150 mL of contrast at 4.5 mL/s). In the second group, reduced contrast volume CTA was performed in patients with "routine" indications (RC group: n = 20, 50-60 mL at 3 mL/s followed by a saline chaser). In both groups, aortic attenuation and SD were measured at 80 and 140 kVp, and the image quality was analyzed using a 5-point scale. The use of DECT postprocessing techniques for assessing aortic pathology was also evaluated. RESULTS: For all patients, the aortic attenuation was significantly higher at 80 kVp than at 140 kVp (P < 0.001). Image noise measured quantitatively was higher at 80 kVp (P < 0.001) but did not affect the perceived image quality (P = 0.3). Using low-peak kilovoltage allowed aortic CTA to be performed with a markedly reduced contrast volume and flow rate, with image quality similar to standard CTA (P = 0.2). In a series of cases with proved aortic disease, comparison of true precontrast and subtraction "virtual noncontrast" images showed the potential to eliminate aortic precontrast imaging, reducing radiation exposure. CONCLUSIONS: Single-acquisition DECT combines (1) the benefits of low-kVp vascular imaging (increased iodine conspicuity coupled with a contrast volume/rate reduction) and (2) the use of material-specific imaging techniques to uniquely characterize the aortic pathology. |
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Authors:
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Myrna C B Godoy; David P Naidich; Edson Marchiori; Christianne Leidecker; Bernhard Schmidt; Bernard Assadourian; Ioannis Vlahos |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of computer assisted tomography Volume: 34 ISSN: 1532-3145 ISO Abbreviation: J Comput Assist Tomogr Publication Date: 2010 Sep-Oct |
Date Detail:
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Created Date: 2010-09-23 Completed Date: 2010-10-19 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7703942 Medline TA: J Comput Assist Tomogr Country: United States |
Other Details:
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Languages: eng Pagination: 670-7 Citation Subset: IM |
Affiliation:
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Division of Thoracic Imaging, Department of Radiology, New York University Langone Medical Center, New York, NY, USA. mgodoy@mdanderson.org |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Aortic Diseases / radiography* Aortography / methods* Contrast Media / administration & dosage Coronary Angiography / methods* Feasibility Studies Female Humans Iohexol / administration & dosage, analogs & derivatives Male Middle Aged Radiation Dosage Radiographic Image Interpretation, Computer-Assisted Statistics, Nonparametric Tomography, X-Ray Computed / methods* |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 66108-95-0/Iohexol; 73334-07-3/iopromide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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