Document Detail


Single-acquisition dual-energy multidetector computed tomography: analysis of vascular enhancement and postprocessing techniques for evaluating the thoracic aorta.
MedLine Citation:
PMID:  20861768     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: The objectives of this study were (1) to evaluate the potential of low-peak kilovoltage (kVp) images acquired with dual-energy computed tomography (DECT) to improve aortic attenuation and reduce contrast agent utilization and (2) to evaluate the feasibility of material-specific DECT imaging for evaluating aortic disease. MATERIALS AND METHODS: Aortic imaging characteristics of 2 groups of patients examined with DECT were compared. In the first group, CT angiography (CTA) was performed in patients with known or suspected aortic disease (CTA group: n = 20, 100-150 mL of contrast at 4.5 mL/s). In the second group, reduced contrast volume CTA was performed in patients with "routine" indications (RC group: n = 20, 50-60 mL at 3 mL/s followed by a saline chaser). In both groups, aortic attenuation and SD were measured at 80 and 140 kVp, and the image quality was analyzed using a 5-point scale. The use of DECT postprocessing techniques for assessing aortic pathology was also evaluated. RESULTS: For all patients, the aortic attenuation was significantly higher at 80 kVp than at 140 kVp (P < 0.001). Image noise measured quantitatively was higher at 80 kVp (P < 0.001) but did not affect the perceived image quality (P = 0.3). Using low-peak kilovoltage allowed aortic CTA to be performed with a markedly reduced contrast volume and flow rate, with image quality similar to standard CTA (P = 0.2). In a series of cases with proved aortic disease, comparison of true precontrast and subtraction "virtual noncontrast" images showed the potential to eliminate aortic precontrast imaging, reducing radiation exposure. CONCLUSIONS: Single-acquisition DECT combines (1) the benefits of low-kVp vascular imaging (increased iodine conspicuity coupled with a contrast volume/rate reduction) and (2) the use of material-specific imaging techniques to uniquely characterize the aortic pathology.
Authors:
Myrna C B Godoy; David P Naidich; Edson Marchiori; Christianne Leidecker; Bernhard Schmidt; Bernard Assadourian; Ioannis Vlahos
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of computer assisted tomography     Volume:  34     ISSN:  1532-3145     ISO Abbreviation:  J Comput Assist Tomogr     Publication Date:    2010 Sep-Oct
Date Detail:
Created Date:  2010-09-23     Completed Date:  2010-10-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7703942     Medline TA:  J Comput Assist Tomogr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  670-7     Citation Subset:  IM    
Affiliation:
Division of Thoracic Imaging, Department of Radiology, New York University Langone Medical Center, New York, NY, USA. mgodoy@mdanderson.org
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Aortic Diseases / radiography*
Aortography / methods*
Contrast Media / administration & dosage
Coronary Angiography / methods*
Feasibility Studies
Female
Humans
Iohexol / administration & dosage,  analogs & derivatives
Male
Middle Aged
Radiation Dosage
Radiographic Image Interpretation, Computer-Assisted
Statistics, Nonparametric
Tomography, X-Ray Computed / methods*
Chemical
Reg. No./Substance:
0/Contrast Media; 66108-95-0/Iohexol; 73334-07-3/iopromide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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