Document Detail

Single Amino Acid Substitution Reveals Latent Photolyase Activity in Arabidopsis cry1.
MedLine Citation:
PMID:  22890584     Owner:  NLM     Status:  Publisher    
A quick switch: A single amino acid substitution at a conserved residue (D396N) of Arabidopsis cryptochrome-1 (Atcry1) confers single-stranded DNA repair activity in vitro, conferring photolyase activity onto the cryptochrome. The mutant protein undergoes photoreduction of flavin to the fully reduced anionic form, similar to photolyases and unlike wild-type cryptochromes.
Sarah Burney; Ringo Wenzel; Tilman Kottke; Thomas Roussel; Nathalie Hoang; Jean-Pierre Bouly; Robert Bittl; Joachim Heberle; Margaret Ahmad
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-8-13
Journal Detail:
Title:  Angewandte Chemie (International ed. in English)     Volume:  -     ISSN:  1521-3773     ISO Abbreviation:  Angew. Chem. Int. Ed. Engl.     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-8-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370543     Medline TA:  Angew Chem Int Ed Engl     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
PCMP, UR5, Université Paris VI, Casier 156, 4 Place Jussieu, 75005 Paris (France).
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