| Simultaneous onset of pemphigus vulgaris in two Turkish siblings. | |
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MedLine Citation:
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PMID: 15863864 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The etiology of pemphigus vulgaris is still unknown. Reported familial cases are indicators of a genetic aspect of the disease. We report a brother and sister with simultaneous onset of pemphigus vulgaris. The class II antigens, HLA DRB1*04 and DQB1*03 were detected in both patients. The oral mucosa was affected in one them. Elevation of transaminase levels due to azathioprine therapy was observed in these two cases. |
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Authors:
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Ayşe Kavak; Ilker Aydoğan; Sevim Gönen |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The Journal of dermatology Volume: 32 ISSN: 0385-2407 ISO Abbreviation: J. Dermatol. Publication Date: 2005 Mar |
Date Detail:
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Created Date: 2005-05-02 Completed Date: 2005-06-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7600545 Medline TA: J Dermatol Country: Japan |
Other Details:
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Languages: eng Pagination: 186-8 Citation Subset: IM |
Affiliation:
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Abant Izzet Baysal University, Duzce Medical School, Department of Dermatology, Duzce, Turkey. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Female Follow-Up Studies Genetic Predisposition to Disease* HLA-DQ Antigens / genetics* HLA-DR Antigens / genetics* Humans Male Mouth Mucosa / pathology Pemphigus / diagnosis*, genetics* Polymorphism, Genetic* Risk Assessment Severity of Illness Index Siblings Turkey |
| Chemical | |
Reg. No./Substance:
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0/HLA-DQ Antigens; 0/HLA-DR Antigens; 128338-86-3/HLA-DRB1 antigen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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