Document Detail


Simultaneous occurrence of chronic lymphocytic and chronic myeloid leukemia.
MedLine Citation:
PMID:  20698147     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The coexistence of chronic lymphocytic (CLL) and chronic myeloid leukemia (CML) in the same patient has only been reported occasionally. Most of these cases represent the patients who developed CLL during the course of CML. Reviewing the literature, only a few cases of simultaneous occurrence of CLL and CML were found. Here we represent a previously healthy 50-year old man in whom the diagnosis of CLL and CML was established by FNAB of the bone marrow. The diagnosis was then confirmed by histopathology, immunophenotypization of the peripheral blood and by a cytogenetic study of the bone marrow. Four years after the diagnosis the patient is well, with leucocytosis of 40 x 10(9)/L, and lymphocytosis of 93%.
Authors:
Sandra Kojić Katović; Ankica Vasilj; Ivana Maricević; Dubravka Carzavec; Silva Curić Jurić
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Collegium antropologicum     Volume:  34     ISSN:  0350-6134     ISO Abbreviation:  Coll Antropol     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-08-11     Completed Date:  2010-09-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8003354     Medline TA:  Coll Antropol     Country:  Croatia    
Other Details:
Languages:  eng     Pagination:  653-5     Citation Subset:  IM    
Affiliation:
Department of Cytology, "Sestre milosrdnice" University Hospital, Zagreb, Croatia. skojic@kbsm.hr
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MeSH Terms
Descriptor/Qualifier:
Antineoplastic Agents / therapeutic use
B-Lymphocytes / immunology,  pathology
Bone Marrow / pathology
Eosinophils / pathology
Humans
Immunoglobulin Heavy Chains / genetics
Leukemia, Lymphocytic, Chronic, B-Cell / complications*,  drug therapy,  genetics,  pathology
Leukemia, Myelogenous, Chronic, BCR-ABL Positive / complications*,  drug therapy,  genetics,  pathology
Lymphocytes / pathology
Male
Middle Aged
Polymerase Chain Reaction
Treatment Outcome
Chemical
Reg. No./Substance:
0/Antineoplastic Agents; 0/Immunoglobulin Heavy Chains

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