Document Detail


Simultaneous measurements of adenosine deaminase activity and tuberculostearic acid in pleural effusions for the diagnosis of tuberculous pleuritis.
MedLine Citation:
PMID:  1392176     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Adenosine deaminase (ADA) activity and tuberculostearic acid (TSA) levels in pleural effusions were measured in 18 patients with active tuberculous pleuritis, 16 patients suspected of having tuberculous pleuritis, 14 patients with carcinomatous pleuritis, and 19 patients suffering from pleuritis of non-malignant and non-tuberculous etiology. In the patients with active tuberculous pleuritis, ADA was elevated in 56% and TSA was positive in 78%. In 83% of these patients, either ADA was elevated or TSA was positive. ADA was elevated together with a positive TSA in 50%. In contrast, TSA was positive in only 6% and ADA was elevated in 24% of the patients with non-tuberculous pleuritis, and none of these patients showed the combination of an elevation of ADA and a positive TSA. These results suggest that simultaneous measurements of both ADA and TSA in pleural effusions are useful for the diagnosis of tuberculous pleuritis.
Authors:
H Muranishi; M Nakashima; H Hirano; T Saitoh; H Takahashi; K Tanaka; M Miyazaki; K Yagawa; N Shigematsu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  31     ISSN:  0918-2918     ISO Abbreviation:  Intern. Med.     Publication Date:  1992 Jun 
Date Detail:
Created Date:  1992-11-13     Completed Date:  1992-11-13     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  752-5     Citation Subset:  IM    
Affiliation:
Research Institute for Diseases of the Chest, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adenosine Deaminase / analysis,  metabolism*
Evaluation Studies as Topic
Humans
Pleural Effusion / metabolism
Sensitivity and Specificity
Stearic Acids / analysis,  metabolism*
Tuberculosis, Pleural / diagnosis*,  metabolism
Chemical
Reg. No./Substance:
0/Stearic Acids; 542-47-2/tuberculostearic acid; EC 3.5.4.4/Adenosine Deaminase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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