| Simultaneous measurement of preferred ambient temperature and metabolism in rats. | |
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MedLine Citation:
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PMID: 3344833 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A recent study from this laboratory found that rats placed in a temperature gradient preferred ambient temperatures (Ta) that were significantly below the lower critical Ta of the thermoneutral zone for elevating metabolic rate (MR). To further evaluate the interaction between preferred Ta and MR in the rat, a system was developed where preferred Ta, MR (i.e., O2 consumption), and activity could be automatically monitored in the unrestrained rat. Two groups of male Sprague-Dawley rats, a light-weight group and a heavy-weight group, were placed in a longitudinal temperature gradient for 90 min. These animals were further divided into two groups. One group was permitted free run in the gradient with a temperature range of 7-40 degrees C, whereas another group was restricted to the warm end of the gradient where the coolest available temperature was approximately equal to the lower critical Ta (29 degrees C). The preferred Ta and MR data were statistically analyzed over the last 20 min of the experimental run. Rats allowed to run freely in the gradient selected Ta of 17-20 degrees C and had MR significantly higher than animals restricted to a range of Ta no cooler than the lower critical Ta. Animals that selected the cooler Ta were much more active than those forced to remain at the warmer Ta. In conclusion, the interaction between behavioral and autonomic thermoregulation in the rat is unique compared with other rodent species such as the mouse, hamster, and guinea pig, which prefer Ta associated with thermoneutrality. |
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Authors:
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C J Gordon |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The American journal of physiology Volume: 254 ISSN: 0002-9513 ISO Abbreviation: Am. J. Physiol. Publication Date: 1988 Feb |
Date Detail:
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Created Date: 1988-03-30 Completed Date: 1988-03-30 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0370511 Medline TA: Am J Physiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: R229-34 Citation Subset: IM |
Affiliation:
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Neurotoxicology Division, US Environmental Protection Agency, Research Triangle Park, North Carolina 27711. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Basal Metabolism Energy Metabolism Male Oxygen Consumption Rats Rats, Inbred Strains / metabolism* Reference Values Temperature* Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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