Document Detail


Simultaneous measurement of antroduodenal motility, gastric emptying, and duodenogastric reflux in man.
MedLine Citation:
PMID:  527873     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In six healthy individuals, the relationship between antroduodenal motor activity, duodenogastric reflux, and gastric emptying were simultaneously examined by combined use of multiple marker perfusion and miniature strain gauge transducers. An interdigestive pattern of motor activity was observed during the fasting period;duodenogastric reflux was of variable magnitude, but reproducible in each individual. Fasting reflux was significantly reduced during phase III of the interdigestive complex. Administration of 0.15 M sodium chloride into the stomach resulted in minor and inconsistent changes in antroduodenal motility, despite the rapid and similar pattern of gastric emptying in the six subjects. This study supports the concept that motor activity in the antroduodenal region does not affect gastric emptying of inert, isotonic fluids but may be involved in the regulation of duodenogastric reflux.
Authors:
W D Rees; V L Go; J R Malagelada
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Gut     Volume:  20     ISSN:  0017-5749     ISO Abbreviation:  Gut     Publication Date:  1979 Nov 
Date Detail:
Created Date:  1980-04-26     Completed Date:  1980-04-26     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985108R     Medline TA:  Gut     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  963-70     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Duodenum / drug effects,  physiology*
Fasting
Gastric Emptying* / drug effects
Gastrointestinal Motility* / drug effects
Humans
Pyloric Antrum / drug effects,  physiology*
Sodium Chloride / pharmacology
Chemical
Reg. No./Substance:
7647-14-5/Sodium Chloride
Comments/Corrections

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