| Simultaneous isolated bilateral facial palsy : A rare vincristine-associated toxicity. | |
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MedLine Citation:
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PMID: 19770526 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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We describe a case of a 15-year-old boy with vincristine-induced simultaneous isolated bilateral facial palsy. The boy presented with superior vena caval syndrome (SVC syndrome), right-sided pleural effusion and anterior mediastinal lymphadenopathy. Histopathological examination of left axillary lymph node was suggestive of lymphoblastic lymphoma. We started chemotherapy with cyclophosphamide, doxorubicin, vincristine and prednisolone. SVC syndrome disappeared completely after the 1st cycle, and he achieved remission after the 3rd cycle of chemotherapy. He noticed that he could not close his eyes. Neurological examination revealed bilateral lower motor neuron facial palsy. Findings from examination of other cranial nerves and peripheral nerves were normal. Results of MRI of brain and cerebrospinal fluid examination were normal. He received 6 mg vincristine before developing toxicity. |
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Authors:
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Supriya Sarkar; Asit Ranjan Deb; Kaushik Saha; Chandra Shekhar Das |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Indian journal of medical sciences Volume: 63 ISSN: 1998-3654 ISO Abbreviation: Indian J Med Sci Publication Date: 2009 Aug |
Date Detail:
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Created Date: 2009-09-22 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0373023 Medline TA: Indian J Med Sci Country: India |
Other Details:
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Languages: eng Pagination: 355-8 Citation Subset: IM |
Affiliation:
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Department of Chest Medicine, NRS Medical College and Hospital, Kolkata, West Bengal, India. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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