Document Detail


Simultaneous MR/PET imaging of the human brain: feasibility study.
MedLine Citation:
PMID:  18710991     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of this study was to apply a magnetic resonance (MR) imaging-compatible positron emission tomographic (PET) detector technology for simultaneous MR/PET imaging of the human brain and skull base. The PET detector ring consists of lutetium oxyorthosilicate (LSO) scintillation crystals in combination with avalanche photodiodes (APDs) mounted in a clinical 3-T MR imager with use of the birdcage transmit/receive head coil. Following phantom studies, two patients were simultaneously examined by using fluorine 18 fluorodeoxyglucose (FDG) PET and MR imaging and spectroscopy. MR/PET data enabled accurate coregistration of morphologic and multifunctional information. Simultaneous MR/PET imaging is feasible in humans, opening up new possibilities for the emerging field of molecular imaging.
Authors:
Heinz-Peter W Schlemmer; Bernd J Pichler; Matthias Schmand; Ziad Burbar; Christian Michel; Ralf Ladebeck; Kirstin Jattke; David Townsend; Claude Nahmias; Pradeep K Jacob; Wolf-Dieter Heiss; Claus D Claussen
Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  Radiology     Volume:  248     ISSN:  1527-1315     ISO Abbreviation:  Radiology     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-08-19     Completed Date:  2008-09-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1028-35     Citation Subset:  AIM; IM    
Copyright Information:
RSNA, 2008
Affiliation:
Department of Diagnostic Radiology, University Hospital Tübingen, Hoppe-Seyler-Strasse 3, D-72076 Tübingen, Germany. heinz-peter.schlemmer@med.uni-tuebingen.de
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Brain / pathology*,  radiography*
Feasibility Studies
Fluorodeoxyglucose F18 / diagnostic use*
Humans
Magnetic Resonance Imaging / methods*
Radiopharmaceuticals / diagnostic use
Reproducibility of Results
Sensitivity and Specificity
Subtraction Technique*
Chemical
Reg. No./Substance:
0/Radiopharmaceuticals; 63503-12-8/Fluorodeoxyglucose F18

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Volume rendering with color coding of tagged stool during endoluminal fly-through CT colonography: e...
Next Document:  Pulmonary emphysema: size distribution of emphysematous spaces on multidetector CT images--compariso...