| Simultaneous estimation of four plasma androgens before and after dynamic tests in women with hirsutism: correlation with long-term therapy. | |
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MedLine Citation:
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PMID: 1002113 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Concentrations of testosterone, delta4-androstenedione, dihydrotestosterone and delta5-androstenediol were measured in 12 patients affected by hirsutism associated with menstrual disorders. Testosterone was elevated in 9 cases, in whom high levels of delta4-androstenedione and dihydrotestosterone was found, and normal in 3 cases, 2 of which presented high values of dihydrotestosterone and one high levels of delta5-androstenediol. In some hirsute females therefore, other androgens, such as dihydrotestosterone and delta5-androstenediol, play a role in the pathogenesis of hirsutism. Dexamethasone and estrogen progestin combinations were administered for dynamic tests, and results in most cases provided useful information in the selection of suitable long-term therapy. |
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Authors:
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F Sciarra; V Toscano; G Concolino; G Sorcini; A Marocchi; C Conti |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Hormone research Volume: 7 ISSN: 0301-0163 ISO Abbreviation: Horm. Res. Publication Date: 1976 |
Date Detail:
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Created Date: 1977-02-16 Completed Date: 1977-02-16 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0366126 Medline TA: Horm Res Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 16-27 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Androgens / blood* Androstenediols / blood Androstenedione / blood Dexamethasone / diagnostic use*, therapeutic use Dihydrotestosterone / blood Estradiol Congeners / diagnostic use*, therapeutic use Female Hirsutism / blood*, drug therapy Humans Male Middle Aged Progesterone Congeners / diagnostic use*, therapeutic use Sex Factors Testosterone / blood |
| Chemical | |
Reg. No./Substance:
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0/Androgens; 0/Androstenediols; 0/Estradiol Congeners; 0/Progesterone Congeners; 50-02-2/Dexamethasone; 521-18-6/Dihydrotestosterone; 58-22-0/Testosterone; 63-05-8/Androstenedione |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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