Document Detail


Simultaneous estimation of four plasma androgens before and after dynamic tests in women with hirsutism: correlation with long-term therapy.
MedLine Citation:
PMID:  1002113     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Concentrations of testosterone, delta4-androstenedione, dihydrotestosterone and delta5-androstenediol were measured in 12 patients affected by hirsutism associated with menstrual disorders. Testosterone was elevated in 9 cases, in whom high levels of delta4-androstenedione and dihydrotestosterone was found, and normal in 3 cases, 2 of which presented high values of dihydrotestosterone and one high levels of delta5-androstenediol. In some hirsute females therefore, other androgens, such as dihydrotestosterone and delta5-androstenediol, play a role in the pathogenesis of hirsutism. Dexamethasone and estrogen progestin combinations were administered for dynamic tests, and results in most cases provided useful information in the selection of suitable long-term therapy.
Authors:
F Sciarra; V Toscano; G Concolino; G Sorcini; A Marocchi; C Conti
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Hormone research     Volume:  7     ISSN:  0301-0163     ISO Abbreviation:  Horm. Res.     Publication Date:  1976  
Date Detail:
Created Date:  1977-02-16     Completed Date:  1977-02-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0366126     Medline TA:  Horm Res     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  16-27     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Androgens / blood*
Androstenediols / blood
Androstenedione / blood
Dexamethasone / diagnostic use*,  therapeutic use
Dihydrotestosterone / blood
Estradiol Congeners / diagnostic use*,  therapeutic use
Female
Hirsutism / blood*,  drug therapy
Humans
Male
Middle Aged
Progesterone Congeners / diagnostic use*,  therapeutic use
Sex Factors
Testosterone / blood
Chemical
Reg. No./Substance:
0/Androgens; 0/Androstenediols; 0/Estradiol Congeners; 0/Progesterone Congeners; 50-02-2/Dexamethasone; 521-18-6/Dihydrotestosterone; 58-22-0/Testosterone; 63-05-8/Androstenedione

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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