Document Detail


Simultaneous determination of dopamine and its oxidized product (aminochrom), by hydrodynamic amperometry and anodic stripping voltammetry, using the metallic palladium and uranalyl hexacyanoferrate coated aluminum electrodes.
MedLine Citation:
PMID:  19963367     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In the present work, the development of an effective electroanalytical strategy for the simultaneous determination of dopamine (DA) and aminochrom (AC) using hydrodynamic amperometry and anodic stripping voltammetry (ASV) on the Al modified electrodes is described. For this purpose the Al electrode is plated with metallic palladium (Pd-Al) by simple dipping procedure and subsequently the uranyl hexacyanoferrate (K(2)UO(2)[Fe(CN)(6)]) is deposited electrochemically on the Pd-Al electrode from a UO(2)(2+)+Fe(CN)(6)(3-) solution. The Pd-Al electrode is used for hydrodynamic amperometric measurement of DA at constant electrode potential of 0.35 V in a stirred electrolyte solution. At fixed operational conditions, the calibration graph for amperometry was linear over the DA concentration range 1x10(-6) to 50x10(-6)M. The detection limit of DA was 4.1x10(-7) M. Whereas the decrease of the ASV current of the K(2)UO(2)[Fe(CN)(6)]/Pd-Al electrode prepared in the presence of AC was the principal of the AC determination. This decrease was proportional to the AC concentration in the solution, during K(2)UO(2)[Fe(CN)(6)]/Pd-Al electrode preparation and the calibration graph was linear over the concentration range 1x10(-6) to 35x10(-6) M of AC. The detection limit was 4.5x10(-7) M AC.
Authors:
M H Pournaghi-Azar; H Dastangoo; R Fadakar bajeh baj
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Publication Detail:
Type:  Evaluation Studies; Journal Article     Date:  2009-11-11
Journal Detail:
Title:  Biosensors & bioelectronics     Volume:  25     ISSN:  1873-4235     ISO Abbreviation:  Biosens Bioelectron     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-02-03     Completed Date:  2010-04-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9001289     Medline TA:  Biosens Bioelectron     Country:  England    
Other Details:
Languages:  eng     Pagination:  1481-6     Citation Subset:  IM    
Copyright Information:
Copyright 2009 Elsevier B.V. All rights reserved.
Affiliation:
Faculty of Chemistry, University of Tabriz, Tabriz, Iran. Pournaghiazar@tabrizu.ac.ir
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MeSH Terms
Descriptor/Qualifier:
Biosensing Techniques / instrumentation*
Coated Materials, Biocompatible / chemistry
Complex Mixtures / analysis
Conductometry / instrumentation*,  methods
Dopamine / analysis*,  chemistry
Electrodes*
Equipment Design
Equipment Failure Analysis
Ferrocyanides / chemistry*
Indolequinones / analysis*,  chemistry
Oxidation-Reduction
Palladium / chemistry*
Reproducibility of Results
Sensitivity and Specificity
Chemical
Reg. No./Substance:
0/Coated Materials, Biocompatible; 0/Complex Mixtures; 0/Ferrocyanides; 0/Indolequinones; 0/ferrocyn; 39984-17-3/aminochrome 1; 7440-05-3/Palladium

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