Document Detail


Simultaneous determination of PCDDs, PCDFs, PCBs and PBDEs in food.
MedLine Citation:
PMID:  18969544     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Established and comprehensively validated methodology for the analysis of PCDDs, PCDFs and polychlorinated biphenyls (PCBs) in food, animal feed and other matrices is presented. The method achieves the analytical standards of EU protocols (2002/69/EC and 2002/70/EC) that are used to determine the compliance of food and animal feed to maximum permissible levels of chlorinated dioxins in these commodities. The methodology provides WHO-TEQ data for dioxins and PCBs as well as individual concentrations for toxic PCDD/F congeners and >50 commonly occurring PCBs. In addition, the methodology allows the simultaneous determination of individual polybrominated diphenylether (PBDE) congeners. A wide range of (13)Carbon -labelled surrogates allow accurate internal standardisation, and measurements are carried out using high resolution GC coupled to high resolution mass spectrometry except for mono-, tetra, ortho-substituted PCBs where unit resolution mass spectrometry can be used instead. Evidence of internal as well as external validation through the frequent use of reference materials, and successful participation in international inter-comparison exercises over many years is presented. A large number of different food types have been analysed for dioxins and PCBs using this methodology over several years and typical congener profiles for various food matrices are discussed.
Authors:
Alwyn Fernandes; Shaun White; Kyle D'Silva; Martin Rose
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Talanta     Volume:  63     ISSN:  1873-3573     ISO Abbreviation:  Talanta     Publication Date:  2004 Aug 
Date Detail:
Created Date:  2008-10-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2984816R     Medline TA:  Talanta     Country:  England    
Other Details:
Languages:  eng     Pagination:  1147-55     Citation Subset:  -    
Affiliation:
Central Science Laboratory, Sand Hutton, York YO41 1LZ, UK.
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