Document Detail


Simultaneous determination of 11 characteristic components in three species of Curcuma rhizomes using pressurized liquid extraction and high-performance liquid chromatography.
MedLine Citation:
PMID:  17018231     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A high-performance liquid chromatography coupled with diode array detection (HPLC-DAD) and pressurized liquid extraction was developed for simultaneous quantitative determination of 11 characteristic compounds, including curcumenone, curcumenol, neocurdione, curdione, isocurcumenol, furanodienone, curcumol, germacrone, curzerene, furanodiene and beta-elemene, in rhizomes of three species of Curcuma. The analysis was performed on an ODS C18 column. The mobile phase consisted of (A) water and (B) acetonitrile using a gradient elution. The peaks were monitored at both 214 nm and 256 nm. All calibration curves showed good linearity (r2 > 0.9996) within test ranges. This method showed good repeatability for the quantification of these eleven components in three species Curcuma rhizomes with intra- and inter-day variations of less than 1.57% and 1.98%, respectively. The validated method was successfully applied to quantify 11 investigated components in eighteen samples of three species of Curcuma, which is helpful to control their quality.
Authors:
F Q Yang; Y T Wang; S P Li
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-10-02
Journal Detail:
Title:  Journal of chromatography. A     Volume:  1134     ISSN:  0021-9673     ISO Abbreviation:  J Chromatogr A     Publication Date:  2006 Nov 
Date Detail:
Created Date:  2006-12-05     Completed Date:  2007-01-04     Revised Date:  2009-01-15    
Medline Journal Info:
Nlm Unique ID:  9318488     Medline TA:  J Chromatogr A     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  226-31     Citation Subset:  IM    
Affiliation:
Institute of Chinese Medical Sciences, University of Macau, Macau, China.
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MeSH Terms
Descriptor/Qualifier:
Acetonitriles / metabolism
Calibration
Chromatography, Gas
Chromatography, High Pressure Liquid
Curcuma / chemistry*,  classification*
Mass Spectrometry
Plant Extracts / analysis*,  chemistry,  isolation & purification*
Regression Analysis
Rhizome / chemistry*
Chemical
Reg. No./Substance:
0/Acetonitriles; 0/Plant Extracts

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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