Document Detail


Simultaneous detection of biomolecular interactions and surface topography using photonic force microscopy.
MedLine Citation:
PMID:  23202338     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
We developed a photonic force microscope that can map multiple parameters simultaneously, including the surface topography and biomolecular interactions. To track the position of the probe bead and to determine contact position with the sample surface, we adopted a video analysis method using the diffraction pattern of monochromatic light passing through the probe bead. To demonstrate the capability of the microscope, we report the simultaneous measurement of the molecule distribution of DNA oligonucleotides on the surface, the binding strength of DNA hybridization between the bead and surface, and the topography of the smooth molded surface.
Authors:
Seungjin Heo; Kipom Kim; Rodriguez Christophe; Tae-Young Yoon; Yong-Hoon Cho
Related Documents :
23752228 - Changes in rna polymerase ii progression influence somatic hypermutation of ig-related ...
23202338 - Simultaneous detection of biomolecular interactions and surface topography using photon...
18769728 - Targeted chromosomal insertion of large dna into the human genome by a fiber-modified h...
11297698 - Identification of a genetic determinant of pathogenicity in chicken anaemia virus.
25085418 - A unique dna entry gate serves for regulated loading of the eukaryotic replicative heli...
19406918 - Circulating methylated sept9 dna in plasma is a biomarker for colorectal cancer.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-22
Journal Detail:
Title:  Biosensors & bioelectronics     Volume:  42C     ISSN:  1873-4235     ISO Abbreviation:  Biosens Bioelectron     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-12-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9001289     Medline TA:  Biosens Bioelectron     Country:  -    
Other Details:
Languages:  ENG     Pagination:  106-111     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier B.V. All rights reserved.
Affiliation:
Graduate School of Nanoscience & Technology (WCU), KAIST, Daejeon 305-701, Republic of Korea.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Zwitterionic polymer-modified silicon microring resonators for label-free biosensing in undiluted hu...
Next Document:  Graphene oxide/poly-l-lysine assembled layer for adhesion and electrochemical impedance detection of...