Document Detail


Simultaneous comparison of tracheobronchial and right duct lymph dynamics in dogs.
MedLine Citation:
PMID:  6826405     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The simultaneous responses of lymph flow and protein concentration were compared using lymph from the right duct (RD) and small afferent tracheobronchial (TB) lymphatics cannulated in the same dog. Lymph was collected during a base-line period and following steady-state left atrial pressure (Pla) elevations. For a mean increase in Pla of 14.8 cmH2O, RD flow increased 1.1 times control and TB flow by 2.5 times control. Total protein lymph-to-plasma ratios decreased significantly for TB lymph but not for RD lymph. Assuming TB represented pure lung lymph, the right duct was estimated to drain 4% of the total lung lymph and consist of 11% lung lymph with 89% extrapulmonary lymph at normal lymph flows. The lung lymph contribution to RD flow increased to 24% with increased Pla. Equivalent capillary pore dimensions calculated using endogenous protein fractions in both RD and TB lymph resulted in small pores of 100 and 90 A and large pores of 220 and 225 A, respectively. The fraction filtered through the large-pore population estimated using RD lymph was half that predicted using TB lymph. These data indicate that RD lymph data cannot accurately reflect pulmonary vascular permeability, since extrapulmonary lymph provided a major component of RD lymph flow at both base-line and increased filtration states.
Authors:
D J Martin; J C Parker; A E Taylor
Related Documents :
24551035 - Characterization of neutrophil subsets in healthy human pregnancies.
24963005 - Assessment of flow distribution in the mouse fetal circulation at late gestation using ...
694415 - Comparative effects of synthetic and natural vasoactive intestinal peptide on pancreati...
2836225 - Food deprivation decreases the blood trh concentration in the rat.
7468035 - Blood flow in experimental liver tumors: effect of vasoactive drugs.
7238425 - The flexible bronchofiberscope in the intensive care unit (icu)--the optimal postoperat...
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of applied physiology: respiratory, environmental and exercise physiology     Volume:  54     ISSN:  0161-7567     ISO Abbreviation:  J Appl Physiol Respir Environ Exerc Physiol     Publication Date:  1983 Jan 
Date Detail:
Created Date:  1983-04-15     Completed Date:  1983-04-15     Revised Date:  2013-09-26    
Medline Journal Info:
Nlm Unique ID:  7801242     Medline TA:  J Appl Physiol Respir Environ Exerc Physiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  199-207     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Blood Pressure
Bronchi / physiology*
Dogs
Lymph / physiology*
Lymphatic System / physiology*
Models, Biological
Time Factors
Trachea / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Axial distortion of airways in the lung.
Next Document:  Ascorbate uptake by isolated rat alveolar macrophages and type II cells.