| Simultaneous assessment of wall motion and coronary flow velocity in the left anterior descending coronary artery during dipyridamole stress echocardiography. | |
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MedLine Citation:
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PMID: 12724655 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVES: This study was designed to assess the feasibility and clinical meaning of simultaneous assessment of wall motion and coronary flow velocity (CFV) reserve in the left anterior descending coronary artery (LAD) by transthoracic approach for detecting LAD stenosis during dipyridamole stress echocardiography. BACKGROUND: Coronary flow reserve plays an important role, which can be evaluated by transthoracic Doppler echocardiography during vasodilator stress. METHODS: Dipyridamole stress test was performed in 110 patients with known or suspected coronary artery disease. CFV in the distal LAD was obtained at baseline and after dipyridamole infusion, and wall motion was also assessed up to the administration of atropine, if required. All patients underwent quantitative coronary angiography within 2 days of the stress test, and significant LAD stenosis was defined as > 50% stenosis. RESULTS: The success rate of both measurements was 92%. CFV reserve < 2 had a higher sensitivity (94% vs 72%, P <.01) and a lower specificity (65% vs 95%, P <.01) than wall-motion assessment for detecting significant LAD stenosis, and diagnostic accuracy between 2 methods was comparable (81% vs 82%). A total of 69 patients (73%) showed concordant results of the 2 methods, and diagnostic accuracy for detecting significant LAD stenosis was high (94%) in this subset of patients. CONCLUSIONS: The simultaneous assessment of CFV and wall motion was feasible in the majority of cases during dipyridamole stress echocardiography. Although diagnostic accuracy between the 2 tests was comparable, concordant results of the 2 methods provided accurate diagnosis in detecting significant LAD stenosis. |
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Authors:
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Yuichi Nohtomi; Masaaki Takeuchi; Kazushige Nagasawa; Ken-ichi Arimura; Kenji Miyata; Kouichi Kuwata; Tohru Yamawaki; Shoichi Kondo; Akira Yamada; Shuichi Okamatsu |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography Volume: 16 ISSN: 0894-7317 ISO Abbreviation: J Am Soc Echocardiogr Publication Date: 2003 May |
Date Detail:
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Created Date: 2003-05-01 Completed Date: 2003-08-26 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8801388 Medline TA: J Am Soc Echocardiogr Country: United States |
Other Details:
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Languages: eng Pagination: 457-63 Citation Subset: IM |
Affiliation:
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Department of Cardiovascular Medicine, Cardiovascular Center, Iizuka Hospital, Japan. notomiy@ccf.org |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Blood Flow Velocity* Constriction, Pathologic Coronary Angiography Coronary Vessels / pathology, physiology* Dipyridamole / diagnostic use Echocardiography, Doppler Feasibility Studies Female Humans Male Middle Aged Myocardial Contraction* Sensitivity and Specificity Vasodilator Agents / diagnostic use |
| Chemical | |
Reg. No./Substance:
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0/Vasodilator Agents; 58-32-2/Dipyridamole |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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