| Simultaneous acral nodular eruption and flagellate erythema caused by bleomycin. | |
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MedLine Citation:
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PMID: 15696989 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 29-year-old male with AIDS was treated with bleomycin and vincristine for visceral Kaposi's sarcoma. Three days later, he developed two distinct eruptions simultaneously. One eruption was characterized by tender, erythematous, edematous plaques and nodules on the palmar and dorsal surfaces of the hands, forearms, and elbows. The other consisted of grouped, erythematous, hyperpigmented streaks on the trunk, buttocks, and extremities. The patient subsequently received a second treatment consisting of vincristine with adriamycin, without bleomycin, and no cutaneous effects were seen. Diagnoses of flagellate erythema and acral nodular eruption secondary to bleomycin were made and confirmed histopathologically. To our knowledge, this is the first report of two cutaneous side effects of bleomycin appearing simultaneously in a patient with AIDS. |
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Authors:
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Maryann Mikhail; Mark Eichenbaum; Eric Gerstenfeld; Julie Duquette; Miriam Keltz Pomeranz; David Polsky |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of drugs in dermatology : JDD Volume: 4 ISSN: 1545-9616 ISO Abbreviation: J Drugs Dermatol Publication Date: 2005 Jan-Feb |
Date Detail:
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Created Date: 2005-02-08 Completed Date: 2005-04-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101160020 Medline TA: J Drugs Dermatol Country: United States |
Other Details:
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Languages: eng Pagination: 81-4 Citation Subset: IM |
Affiliation:
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The Ronald O. Perelman Department of Dermatology, New York University Medical Center, New York, NY, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acquired Immunodeficiency Syndrome
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complications Adult Anti-Bacterial Agents / adverse effects*, therapeutic use Antineoplastic Agents, Phytogenic / therapeutic use Bleomycin / adverse effects*, therapeutic use Doxorubicin / therapeutic use Drug Eruptions / pathology* Erythema / chemically induced*, pathology* Humans Male Sarcoma, Kaposi / drug therapy Skin / pathology* Vincristine / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Anti-Bacterial Agents; 0/Antineoplastic Agents, Phytogenic; 11056-06-7/Bleomycin; 23214-92-8/Doxorubicin; 57-22-7/Vincristine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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