| Simultaneous acquisition of gradient echo/spin echo BOLD and perfusion with a separate labeling coil. | |
| | |
MedLine Citation:
|
PMID: 20648682 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Arterial spin labeling-based cerebral blood flow imaging complements blood oxygenation level dependent (BOLD) imaging with a measure that is more quantitative and has better specificity to neuronal activation. Relative to gradient echo BOLD, spin echo BOLD has better spatial specificity because it is less biased to large draining veins. Although there have been many studies comparing simultaneously acquired cerebral blood flow data with gradient echo BOLD data in fMRI, there have been few studies comparing cerebral blood flow with SE BOLD and no study comparing all three. We present a pulse sequence that simultaneously acquires cerebral blood flow data with a separate labeling coil, gradient echo BOLD, and spin echo BOLD images. Simultaneous acquisition avoids interscan variability, allowing more direct assessment and comparison of each contrast's relative specificity and reproducibility. Furthermore, it facilitates studies that may benefit from multiple complementary measures. |
| | |
Authors:
|
C B Glielmi; Q Xu; R C Craddock; X Hu |
Publication Detail:
|
Type: Journal Article; Research Support, N.I.H., Extramural |
Journal Detail:
|
Title: Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine Volume: 64 ISSN: 1522-2594 ISO Abbreviation: Magn Reson Med Publication Date: 2010 Dec |
Date Detail:
|
Created Date: 2010-11-25 Completed Date: 2011-04-19 Revised Date: 2011-12-21 |
Medline Journal Info:
|
Nlm Unique ID: 8505245 Medline TA: Magn Reson Med Country: United States |
Other Details:
|
Languages: eng Pagination: 1827-31 Citation Subset: IM |
Copyright Information:
|
© 2010 Wiley-Liss, Inc. |
Affiliation:
|
Department of Biomedical Engineering, Georgia Institute of Technology/Emory University, Atlanta, Georgia, USA. christopher.glielmi@siemens.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Algorithms Cerebrovascular Circulation / physiology* Humans Magnetic Resonance Imaging / instrumentation*, methods* Male Oxygen / blood Photic Stimulation |
| Grant Support | |
ID/Acronym/Agency:
|
R01 EB002009/EB/NIBIB NIH HHS; R01 EB002009-08/EB/NIBIB NIH HHS |
| Chemical | |
Reg. No./Substance:
|
7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Delayed contrast-enhanced MRI of cartilage: comparison of nonionic and ionic contrast agents.
Next Document: The biodistribution of [153Gd]Gd-labeled magnetic resonance contrast agents in a transgenic mouse mo...