Document Detail

Simultaneous Ultrasound Assessment of Brachial Artery Shear Stimulus and Flow-Mediated Dilation During Reactive Hyperemia.
MedLine Citation:
PMID:  21821350     Owner:  NLM     Status:  Publisher    
In flow-mediated dilation (FMD) studies, brachial artery diameter changes due to reactive hyperaemia are typically measured through manual or automatic analysis of high resolution B-mode images while the stimulus of diameter change, i.e., the flow change, is qualitatively estimated by measuring the mean velocity in the vessel and assuming a parabolic velocity profile. This article describes an experimental approach to simultaneously measure the wall shear rate (WSR) and the diameter variations, through multigate spectral Doppler and B-mode image processing, respectively. By using an ultrasound advanced open platform (ULA-OP), experimental results from the brachial arteries of 15 presumed healthy volunteers have been obtained. The mean increments during reflow against baseline were 105% ± 22% for the peak WSR and 8% ± 3% for the FMD. The mean time interval between the WSR peak and the beginning of plateau of diameter waveform was 38 ± 8 s. The results confirm that in young healthy subjects the postischemic vasodilation of brachial artery is largely correlated to the WSR increase.
Piero Tortoli; Carlo Palombo; Lorenzo Ghiadoni; Giacomo Bini; Lorenzo Francalanci
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-8-5
Journal Detail:
Title:  Ultrasound in medicine & biology     Volume:  -     ISSN:  1879-291X     ISO Abbreviation:  -     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-8-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0410553     Medline TA:  Ultrasound Med Biol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.
Department of Electronics and Telecommunications, Università degli Studi di Firenze, Firenze, Italy.
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