Document Detail


Simulation study on bypass and therapeutic occlusion in the posterior circulation.
MedLine Citation:
PMID:  7754845     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A hydraulic vascular model of the vertebrobasilar artery with an autoregulatory mechanism was constructed. The haemodynamic effect of superficial temporal artery (STA)-posterior cerebral artery (PCA) bypass was investigated in cases of bilateral vertebral artery (VA) occlusion and basilar artery (BA) occlusion. Assuming therapeutic BA occlusion for basilar bifurcation aneurysms, the flow volume through the P1 segment of the PCA was determined in relation to diameters of the posterior communicating artery (PCom). The bypass increases both flow volume and intraluminal pressure in the presence range below 60 mm Hg, while it increases only pressure in the autoregulatory range above 60 mm Hg. Its haemodynamic effect is more marked in BA occlusion than in VA occlusion. The averaged values of the increase in flow volume are 29.0 +/- 4.3% (mean +/- SD) and 16.5 + 1.0%, respectively. The total flow volume increase of the vertebrobasilar system is usually lower than the flow volume measured at the bypassed STA. The difference between the two is equal to the simultaneous decrease in flow volume through the PComs. Flow volume through the P1 segment can be expressed as a function of the PComs diameter ratio squared. A hydraulic simulation study will be useful for speculating on the haemodynamic effects of these operative procedures.
Authors:
S Nagasawa; T Ohta; H Kikuchi; S Nagayasu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta neurochirurgica     Volume:  132     ISSN:  0001-6268     ISO Abbreviation:  Acta Neurochir (Wien)     Publication Date:  1995  
Date Detail:
Created Date:  1995-06-21     Completed Date:  1995-06-21     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0151000     Medline TA:  Acta Neurochir (Wien)     Country:  AUSTRIA    
Other Details:
Languages:  eng     Pagination:  120-6     Citation Subset:  IM    
Affiliation:
Department of Neurosurgery, Osaka Medical College, Takatsuki, Japan.
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MeSH Terms
Descriptor/Qualifier:
Basilar Artery / physiopathology
Blood Flow Velocity / physiology
Blood Pressure / physiology
Blood Volume / physiology
Brain / blood supply*
Cerebral Revascularization*
Homeostasis / physiology*
Humans
Models, Cardiovascular*
Postoperative Complications / physiopathology*
Vertebral Artery / physiopathology
Vertebrobasilar Insufficiency / physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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