Document Detail

Simulation of normal cardiovascular system and severe aortic stenosis using equivalent electronic model.
MedLine Citation:
PMID:  21047728     Owner:  NLM     Status:  In-Data-Review    
OBJECTIVE: In this study, we have designed an analog circuit model of the cardiovascular system that is able to simulate normal condition and cardiovascular diseases, such as mitral stenosis, aortic stenosis, and hypertension. Especially we focused on severe aortic stenosis, because it is one of the causes of sudden death in asymptomatic patients. In this study, we aim to investigate the simulation of the cardiovascular system using an electronic circuit model under normal and especially severe aortic valve stenosis conditions.
METHODS: The Westkessel model including RLC pi-segments is chosen in order to simulate both systemic and pulmonary circulation. The left and right heart is represented by trapezoidal shape stiffnesses. Aortic capacitance and aortic valve characteristics are chosen nonlinear. Severe aortic stenosis is implemented by changing the value of the serial resistance to the aortic valve. MATLAB® software program is used for the model implementation.
RESULTS: The results for normal conditions of the given electrical model are similar to the normal cardiovascular physiology. As a result of simulation, a remarkable increase of the left ventricle systolic blood pressure and aortic mean pressure gradient, and decrease of aortic systolic blood pressure are observed in severe aortic valve stenosis.
CONCLUSION: In conclusion, our model is effective and available for simulating normal cardiac conditions and cardiovascular diseases, especially severe aortic stenosis.
Mehmet Korürek; Mustafa Yıldız; Ayhan Yüksel
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Publication Detail:
Type:  Journal Article     Date:  2010-11-04
Journal Detail:
Title:  Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology     Volume:  10     ISSN:  1308-0032     ISO Abbreviation:  Anadolu Kardiyol Derg     Publication Date:  2010  
Date Detail:
Created Date:  2010-11-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101095069     Medline TA:  Anadolu Kardiyol Derg     Country:  Turkey    
Other Details:
Languages:  eng     Pagination:  471-8     Citation Subset:  IM    
Faculty of Electrical and Electronic Engineering, İstanbul Technical University, İstanbul, Turkey.
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