| Simulating human cones from mid-mesopic up to high-photopic luminances. | |
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MedLine Citation:
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PMID: 17461685 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A computational model of human cones for intensities ranging from 1 td up to full bleaching levels is presented. The model conforms well with measurements made in primate horizontal cells, follows Weber's law at high intensities, and performs range compression consistent with what is known of cones in other vertebrates. The model consists entirely of processes with a clear physiological interpretation: pigment bleaching, saturation of cGMP hydrolysis, calcium feedback on cGMP synthesis, and a nonlinear membrane. The model is implemented according to a very fast computational scheme useful for simulations, and sample programs in Matlab and Fortran are provided as supplementary material. |
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Authors:
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J H van Hateren; H P Snippe |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2007-03-05 |
Journal Detail:
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Title: Journal of vision Volume: 7 ISSN: 1534-7362 ISO Abbreviation: J Vis Publication Date: 2007 |
Date Detail:
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Created Date: 2007-04-27 Completed Date: 2007-05-08 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 101147197 Medline TA: J Vis Country: United States |
Other Details:
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Languages: eng Pagination: 1 Citation Subset: IM |
Affiliation:
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Netherlands Institute for Neuroscience, Royal Netherlands Academy of Arts and Sciences, Amsterdam, The Netherlands. j.h.van.hateren@rug.nl |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adaptation, Physiological Animals Calcium / metabolism Computer Simulation* Contrast Sensitivity / physiology Cyclic GMP / biosynthesis, metabolism Feedback, Physiological Humans Hydrolysis Light* Macaca Membranes / physiology Models, Neurological* Nonlinear Dynamics Photic Stimulation / methods Retinal Cone Photoreceptor Cells / metabolism, physiology*, radiation effects* Retinal Horizontal Cells / physiology Retinal Pigments / physiology |
| Chemical | |
Reg. No./Substance:
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0/Retinal Pigments; 7440-70-2/Calcium; 7665-99-8/Cyclic GMP |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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