| Simulated meal test. A new method for estimation of parietal and non-parietal secretion in response to food. | |
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MedLine Citation:
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PMID: 3922047 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In ten healthy volunteers gastric secretion was stimulated by a simulated meal, in which the cephalic phase was activated by modified sham feeding and the gastric phase by repeated instillations and withdrawals of a meat soup. The gastric aspirates were analyzed for acid and pepsin and the outputs quantitated by the recovery of an unabsorbable marker (polyethylene glycol). Instillation of liquid meal without sham feeding produced 58% and 65% of pentagastrin-stimulated secretion of acid and pepsin, respectively. Concomitant sham feeding increased the stimulation further, so that the outputs evoked by the combined stimulus (simulated meal test) were similar to that achieved by the pentagastrin test. The coefficient of variation of duplicate tests was 4.5% for acid and 5.4% for pepsin output. The technique is suitable for measuring both parietal and non-parietal secretion in response to food. |
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Authors:
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K Frislid; A Berstad; I Guldvog |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Scandinavian journal of gastroenterology Volume: 20 ISSN: 0036-5521 ISO Abbreviation: Scand. J. Gastroenterol. Publication Date: 1985 Jan |
Date Detail:
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Created Date: 1985-06-03 Completed Date: 1985-06-03 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0060105 Medline TA: Scand J Gastroenterol Country: NORWAY |
Other Details:
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Languages: eng Pagination: 115-22 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Female Food* Gastric Juice / secretion* Gastric Mucosa / secretion* Humans Male Methods Parietal Cells, Gastric / metabolism* Pentagastrin / analysis Pepsin A / secretion Solutions |
| Chemical | |
Reg. No./Substance:
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0/Solutions; 5534-95-2/Pentagastrin; EC 3.4.23.1/Pepsin A |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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