Document Detail


Simulated characterization of atherosclerotic lesions in the coronary arteries by measurement of bioimpedance.
MedLine Citation:
PMID:  12848360     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
FEM software was used to determine the feasibility of characterizing various types of atherosclerotic lesions in vivo. This was accomplished by simulating two electrodes as being attached to an angioplasty balloon in the coronary artery. The electrodes on the "balloon" touched and measured the simulated complex impedance of type III, IV, and Va and Vb lesions, as defined by the American Heart Association (AHA). Additionally, the effect of changes in morphology on the complex impedance was determined for type Va and Vb lesions. The simulations showed that the layer closest to the electrodes had the most significant effect on the measured complex impedance. As a consequence of these simulations, it appears plausible that electrodes could be placed in vivo to determine the characteristics and type of a given atherosclerotic lesion.
Authors:
David K Stiles; Barbara Oakley
Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  IEEE transactions on bio-medical engineering     Volume:  50     ISSN:  0018-9294     ISO Abbreviation:  IEEE Trans Biomed Eng     Publication Date:  2003 Jul 
Date Detail:
Created Date:  2003-07-09     Completed Date:  2003-08-20     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0012737     Medline TA:  IEEE Trans Biomed Eng     Country:  United States    
Other Details:
Languages:  eng     Pagination:  916-21     Citation Subset:  IM    
Affiliation:
Department of Electrical and Systems Engineering, Oakland University, 169 Dodge Hall of Engineering, Rochester, MI 48309, USA. dkstiles@oakland.edu
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MeSH Terms
Descriptor/Qualifier:
Arteries / physiopathology*
Balloon Dilatation / methods
Computer Simulation
Coronary Artery Disease / classification*,  diagnosis*,  physiopathology
Coronary Vessels / physiopathology
Diagnosis, Computer-Assisted / methods
Electric Impedance / diagnostic use*
Feasibility Studies
Humans
Models, Cardiovascular*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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