| Simpson's paradox and the association between vitamin D deficiency and increased heart disease. | |
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MedLine Citation:
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PMID: 22464214 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Several recent investigations have highlighted a potential link between vitamin D deficiency and increased heart disease. Observational studies suggest cardioprotective benefits related to supplementation, but randomized trials remain to be conducted. This report adds a caution based on a statistical paradox that is rarely mentioned in formal medical training or in common medical journals. Insight into this phenomenon, termed Simpson's paradox, may prevent clinicians from drawing faulty conclusions about vitamin D deficiency and heart disease. |
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Authors:
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William K Chan; Donald A Redelmeier |
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Publication Detail:
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Type: Editorial Date: 2012-03-29 |
Journal Detail:
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Title: The American journal of cardiology Volume: 110 ISSN: 1879-1913 ISO Abbreviation: Am. J. Cardiol. Publication Date: 2012 Jul |
Date Detail:
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Created Date: 2012-06-18 Completed Date: 2012-09-04 Revised Date: 2013-02-13 |
Medline Journal Info:
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Nlm Unique ID: 0207277 Medline TA: Am J Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 143-4 Citation Subset: AIM; IM |
Copyright Information:
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Copyright © 2012 Elsevier Inc. All rights reserved. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Dietary Supplements Heart Diseases / epidemiology, etiology*, prevention & control Humans Incidence Ontario / epidemiology Vitamin D / administration & dosage Vitamin D Deficiency / blood, complications*, epidemiology Vitamins / administration & dosage |
| Chemical | |
Reg. No./Substance:
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0/Vitamins; 1406-16-2/Vitamin D |
| Comments/Corrections | |
Comment In:
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Am J Cardiol. 2013 Jan 15;111(2):303-4
[PMID:
23290603
]
Am J Cardiol. 2013 Jan 15;111(2):302-3 [PMID: 23290602 ] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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