Document Detail

Simplifying the process for identifying drug combinations by drug recognition experts.
MedLine Citation:
PMID:  20872299     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The purpose of this study is to statistically identify the set of drug-related cues from Drug Evaluation and Classification (DEC) evaluations that significantly predict the categories of drugs used by suspected drug-impaired drivers. METHODS: Data from 819 completed Canadian DEC evaluations of combinations of central nervous system (CNS) stimulants with cannabis, CNS stimulants with narcotic analgesics, cannabis with alcohol, and no-drug cases were analyzed using a multinomial logistic regression procedure. RESULTS: Eleven clinical indicators from the DEC evaluations significantly enhanced the prediction of drugs used by suspected drug-impaired drivers, including condition of the eyes, lack of convergence, rebound dilation, reaction to light, mean pulse rate, presence of visible injection sites, performance on the Horizontal Gaze Nystagmus Test, pupil size in darkness, performance on the One-Leg Stand Test, muscle tone, and performance on the Walk-and-Turn Test. CONCLUSIONS: The findings from this study will facilitate the process of identifying the correct categories of drugs ingested by suspected drug-impaired drivers by focusing on critical signs and symptoms of drug influence. This work will have direct and immediate relevance to the training of drug recognition experts (DREs) by providing the foundation for an innovative, statistically based approach to drug classification decisions by DREs. This research will also facilitate the enforcement of drug-impaired driving laws in Canada to help make Canadian roadways safer for all.
Amy J Porath-Waller; Douglas J Beirness
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Traffic injury prevention     Volume:  11     ISSN:  1538-957X     ISO Abbreviation:  Traffic Inj Prev     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-09-27     Completed Date:  2010-11-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101144385     Medline TA:  Traffic Inj Prev     Country:  England    
Other Details:
Languages:  eng     Pagination:  453-9     Citation Subset:  IM    
Canadian Centre on Substance Abuse, Ottawa, Ontario, Canada.
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MeSH Terms
Analysis of Variance
Automobile Driving / legislation & jurisprudence*
Central Nervous System Stimulants*
Drug Combinations
Logistic Models
Predictive Value of Tests
Substance Abuse Detection / methods*,  statistics & numerical data
Substance-Related Disorders / diagnosis
Reg. No./Substance:
0/Central Nervous System Stimulants; 0/Drug Combinations; 0/Narcotics; 64-17-5/Ethanol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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