| Simplified method for the measurement of segmental colonic transit time. | |
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MedLine Citation:
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PMID: 8063227 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Segmental colonic transit has been measured in 101 patients. Two MBq of 111Indium absorbed on resin pellets and encapsulated in an enteric coated capsule was given at 7 00 am. Hourly images during the first day, and three images during each subsequent day were acquired for up to three days. Using all scan and patient data the scans were categorised in one of the five patterns of colonic transit: normal, rapid, right delay, left delay, or generalised delay. The geometric centres and per cent activity at each time point was compared between the five groups of colonic transit patients to find the best time for imaging and so to distinguish the five groups. During the first day, early images did not help in diagnosis of patterns of transit, however, in the later images (six hours onwards after the ingestion of the activity) the rapid transit groups could be identified. Images at 27 and 51 hours were both required to distinguish all five groups of patients from each other. Only in the 'normal' transit patients was there some excretion of the activity during the course of the second day, otherwise there was no difference in the images taken in the course of a day (second or third day). A simplified protocol requires a minimum of three images to distinguish all five patterns of colonic transit. The activity should be ingested in the morning (7 00 am) and the first image taken at the end of the working day (8-10 hours after ingestion), the second image on the morning of the second day, and the third image during the course of the third day. This simple protocol would provide all the clinically relevant information necessary for correct classification of the colonic transit. |
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Authors:
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A Notghi; R Hutchinson; D Kumar; N B Smith; L K Harding |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Gut Volume: 35 ISSN: 0017-5749 ISO Abbreviation: Gut Publication Date: 1994 Jul |
Date Detail:
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Created Date: 1994-09-19 Completed Date: 1994-09-19 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 2985108R Medline TA: Gut Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 976-81 Citation Subset: AIM; IM |
Affiliation:
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Department of Physics and Nuclear Medicine, Dudley Road Hospital, Birmingham. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Child Colon / physiopathology*, radionuclide imaging Colonic Diseases / physiopathology*, radionuclide imaging Female Gastroenterology / methods* Gastrointestinal Transit / physiology* Humans Indium Radioisotopes / diagnostic use Male Middle Aged |
| Chemical | |
Reg. No./Substance:
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0/Indium Radioisotopes |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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