Document Detail


Simple intervention method to reduce fumonisin exposure in a subsistence maize-farming community in South Africa.
MedLine Citation:
PMID:  20835935     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In the Centane magisterial area of South Africa, high rates of oesophageal cancer have been associated with home-grown maize contaminated with fumonisins. The aim of this study was to implement a simple intervention method to reduce fumonisin exposure in a subsistence-farming community. The hand-sorting and washing procedures, based on traditional maize-based food preparation practices, were previously customised under laboratory-controlled conditions. Home-grown maize and maize-based porridge collected at baseline were analysed for fumonisin B(1), B(2) and B(3). The geometric mean (95% confidence interval) of fumonisin contamination in the home-grown maize at baseline was 1.67 (1.21-2.32) mg kg(-1) and 1.24 (0.75-2.04) mg kg(-1) (dry weight) in the porridge. Fumonisin exposure was based on individual stiff porridge consumption and the specific fumonisin levels in the porridge (dry weight) consumed. Porridge (dry weight) consumption at baseline was 0.34 kg day(-1) and fumonisin exposure was 6.73 (3.90-11.6) µg kg(-1) body weight day(-1). Female participants (n = 22) were trained to recognise and remove visibly infected/damaged kernels and to wash the remaining maize kernels. The discarded kernels represented 3.9% by weight and the fumonisins varied from 17.1 to 76.9 mg kg(-1). The customised hand-sorting and washing procedures reduced fumonisin contamination in the maize and porridge by 84 and 65%, respectively. The intervention reduced fumonisin exposure by 62% to 2.55 (1.94-3.35) µg kg(-1) body weight day(-1). This simple intervention method has the potential to improve food safety and health in subsistence-farming communities consuming fumonisin-contaminated maize as their staple diet.
Authors:
L van der Westhuizen; G S Shephard; J P Rheeder; H-M Burger; W C A Gelderblom; C P Wild; Y Y Gong
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment     Volume:  27     ISSN:  1944-0057     ISO Abbreviation:  Food Addit Contam Part A Chem Anal Control Expo Risk Assess     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-09-13     Completed Date:  2011-01-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101485040     Medline TA:  Food Addit Contam Part A Chem Anal Control Expo Risk Assess     Country:  England    
Other Details:
Languages:  eng     Pagination:  1582-8     Citation Subset:  IM    
Affiliation:
PROMEC Unit, Medical Research Council, Tygerberg 7505, South Africa. liana.van.der.westhuizen@mrc.ac.za
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Esophageal Neoplasms / prevention & control
Female
Food Contamination / prevention & control*
Food Handling*
Food Inspection*
Fumonisins / administration & dosage,  analysis*
Humans
Middle Aged
Patient Education as Topic
Rural Health*
Seeds / chemistry*
South Africa
Young Adult
Zea mays / chemistry*
Grant Support
ID/Acronym/Agency:
ES06052/ES/NIEHS NIH HHS
Chemical
Reg. No./Substance:
0/Fumonisins; 116355-83-0/fumonisin B1; 116355-84-1/fumonisin B2; 136379-59-4/fumonisin B3

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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