Document Detail

Simple instructions for using pressurized aerosol bronchodilators.
MedLine Citation:
PMID:  7241435     Owner:  NLM     Status:  MEDLINE    
Although the manufacturers of pressurized aerosol bonchodilators issue instructions for using the inhalers, little or no experimental verification exists. Bronchodilatation has been measured after controlled inhalations of 500 μg terbutaline sulphate given in a systematic series of investigations to 8 patients with reversible airways obstruction at 2 different inhalation flow rates (25 1/min and 80 1/min), 3 different lung volumes (20%, 50% and 80% vital capacity) and followed by 2 different breath-holding pauses (4 and 10 seconds). The results indicate that patients may release the aerosol at any time during the course of a slow deep inhalation which should be followed by 10 seconds of breath-holding. This will ensure an optimal bronchodilator response.
S P Newman; D Pavia; S W Clarke
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Journal of the Royal Society of Medicine     Volume:  73     ISSN:  0141-0768     ISO Abbreviation:  J R Soc Med     Publication Date:  1980 Nov 
Date Detail:
Created Date:  1981-08-10     Completed Date:  1981-08-10     Revised Date:  2010-10-26    
Medline Journal Info:
Nlm Unique ID:  7802879     Medline TA:  J R Soc Med     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  776-9     Citation Subset:  IM    
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MeSH Terms
Airway Obstruction / drug therapy
Bronchodilator Agents / administration & dosage*
Patient Education as Topic
Respiratory Therapy / methods*
Terbutaline / administration & dosage
Reg. No./Substance:
0/Aerosols; 0/Bronchodilator Agents; 23031-25-6/Terbutaline

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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