| Simple closure or vagotomy and pyloroplasty for the treatment of a perforated duodenal ulcer: comparison of results. | |
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MedLine Citation:
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PMID: 10867454 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND/AIMS: Treatment of the perforated duodenal ulcer continues to be a controversial subject. The purpose of our study was to compare the results of simple closure of perforated duodenal ulcer versus treatment by truncal vagotomy and pyloroplasty. METHODS: We present a prospective and randomized study of 207 patients who underwent surgical treatment due to perforated duodenal ulcer. In 117 patients the surgical treatment was simple closure and postsurgery medical treatment with proton pump inhibitors for 1 month, and in 90 patients vagotomy and pyloroplasty with no additional medical treatment. RESULTS: We applied the Visick scale in order to compare postsurgery results. The postoperative morbidity and mortality rates were the same with both techniques. Statistically, in both cases, no significant differences were found in postsurgery symptomatology. The different rates of recurrent ulcers and the reinterventions due to recurrent ulcers presented no significant statistical values. CONCLUSION: We conclude that simple closure remains the selected treatment in the majority of patients who present with a perforated duodenal ulcer. The operation is a simple and safe procedure. |
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Authors:
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C Gutiérrez de la Peña; R Márquez; F Fakih; E Domínguez-Adame; J Medina |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: Digestive surgery Volume: 17 ISSN: 0253-4886 ISO Abbreviation: Dig Surg Publication Date: 2000 |
Date Detail:
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Created Date: 2000-08-23 Completed Date: 2000-08-23 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8501808 Medline TA: Dig Surg Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 225-8 Citation Subset: IM |
Copyright Information:
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Copyright 2000 S. Karger AG, Basel |
Affiliation:
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Department of Surgery, Jerez de la Frontera University Hospital, Jerez de la Frontera, Spain. carlosgutierrez@ctv.es |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Duodenal Ulcer / complications* Female Humans Intestinal Perforation / surgery* Male Middle Aged Postoperative Complications Prospective Studies Proton Pumps / antagonists & inhibitors Pyloric Antrum / surgery Recurrence Reoperation Treatment Outcome Vagotomy* |
| Chemical | |
Reg. No./Substance:
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0/Proton Pumps |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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