| A Simple Computational Cell: Coupling Boolean Gene and Protein Networks. | |
| | |
MedLine Citation:
|
PMID: 22356156 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Abstract This article presents an abstract, tunable model containing two of the principal information-processing features of cells and explores its use with simulated evolution. The random Boolean model of genetic regulatory networks is extended to include a protein interaction network. The underlying behavior of the resulting two coupled dynamical networks is investigated before their evolvability is explored using a version of the NK model of fitness landscapes. |
| | |
Authors:
|
Larry Bull |
Related Documents
:
|
21819826 - Predicting accident frequency at their severity levels and its application in site rank... 22446816 - Strategies for the optimisation of in vivo experiments in accordance with the 3rs philo... 22414116 - Rasch analysis of items from two self-report measures of motor function: determination ... 22905276 - Spatial heterogeneity and risk maps of community infestation by triatoma infestans in r... 12421686 - A model for pkc involvement in the pathogenesis of inborn errors of metabolism. 19820056 - An animal breeding approach to the estimation of genetic and environmental trends from ... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-2-22 |
Journal Detail:
|
Title: Artificial life Volume: - ISSN: 1064-5462 ISO Abbreviation: - Publication Date: 2012 Feb |
Date Detail:
|
Created Date: 2012-2-23 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9433814 Medline TA: Artif Life Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
University of the West of England. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Evolvable Physical Self-Replicators.
Next Document: Complete mucostatic impression: a new attempt.