Document Detail


Similar time course of ST depression during and after exercise in patients with coronary artery disease and syndrome X.
MedLine Citation:
PMID:  2220537     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To assess whether the time course of ST segment depression differs in patients with coronary artery disease and patients with angina and normal coronary arteries, the exercise tests of 54 patients with documented coronary artery disease and 25 patients with syndrome X (angina, positive exercise test, no evidence of coronary artery spasm, and normal coronary arteries) were compared. All tests were performed with therapy withheld, using the modified Bruce protocol. In each test, time, heart rate and blood pressure were measured at the onset and at 1 mm of ST segment depression, and at peak exercise. Recovery (return of the ST segment to baseline +/- 0.2 mm) time was also assessed. Peak ST segment depression was similar in coronary artery disease and syndrome X patients (1.5 +/- 0.3 versus 1.6 +/- 0.4 mm). In 42 coronary artery disease patients, ST segment depression developed early (less than or equal to 6 minutes) during exercise; this was associated with a short recovery (less than or equal to 3 minutes) in 17 (40%) and with a long recovery (greater than 3 minutes) in 25 (60%) patients. In 17 patients with syndrome X, ST segment depression developed early; it was associated with a short recovery in six (35%) and with a long recovery in 11 (65%) patients. Late (greater than 6 minutes) onset of ST segment depression was observed in 12 coronary artery disease patients; of these, eight (67%) had a short recovery and 4 (33%) had a long recovery. Late onset of ST segment depression occurred in eight patients with syndrome X; six (75%) had a short recovery and two (25%) had a long recovery.(ABSTRACT TRUNCATED AT 250 WORDS)
Authors:
G Pupita; J C Kaski; A R Galassi; S Gavrielides; F Crea; A Maseri
Related Documents :
18560057 - Detection of st segment deviation episodes in ecg using klt with an ensemble neural cla...
14715347 - Usefulness of compensatory hyperkinesis in the noninfarcted left ventricular wall in se...
6218967 - St-t segment changes in patients with essential hypertension.
6258417 - Right ventricular infarction: relationships between st segment elevation in v4r and hem...
10350197 - Cobalt-55 positron emission tomography in recurrent ischaemic stroke.
6479187 - Flail tricuspid leaflet in childhood--a possible cause of supraventricular tachycardia.
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  American heart journal     Volume:  120     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1990 Oct 
Date Detail:
Created Date:  1990-11-05     Completed Date:  1990-11-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  848-54     Citation Subset:  AIM; IM    
Affiliation:
Cardiovascular Unit, Hammersmith Hospital, London, England.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Angina Pectoris / diagnosis,  physiopathology*
Coronary Disease / diagnosis,  physiopathology*
Electrocardiography*
Exercise Test*
Female
Humans
Male
Middle Aged
Syndrome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Comparison of coronary angiography and early oral dipyridamole thallium-201 scintigraphy in patients...
Next Document:  Prolongation of ventricular refractoriness by class Ia antiarrhythmic drugs in the prevention of ven...