Document Detail

Similar time course of ST depression during and after exercise in patients with coronary artery disease and syndrome X.
MedLine Citation:
PMID:  2220537     Owner:  NLM     Status:  MEDLINE    
To assess whether the time course of ST segment depression differs in patients with coronary artery disease and patients with angina and normal coronary arteries, the exercise tests of 54 patients with documented coronary artery disease and 25 patients with syndrome X (angina, positive exercise test, no evidence of coronary artery spasm, and normal coronary arteries) were compared. All tests were performed with therapy withheld, using the modified Bruce protocol. In each test, time, heart rate and blood pressure were measured at the onset and at 1 mm of ST segment depression, and at peak exercise. Recovery (return of the ST segment to baseline +/- 0.2 mm) time was also assessed. Peak ST segment depression was similar in coronary artery disease and syndrome X patients (1.5 +/- 0.3 versus 1.6 +/- 0.4 mm). In 42 coronary artery disease patients, ST segment depression developed early (less than or equal to 6 minutes) during exercise; this was associated with a short recovery (less than or equal to 3 minutes) in 17 (40%) and with a long recovery (greater than 3 minutes) in 25 (60%) patients. In 17 patients with syndrome X, ST segment depression developed early; it was associated with a short recovery in six (35%) and with a long recovery in 11 (65%) patients. Late (greater than 6 minutes) onset of ST segment depression was observed in 12 coronary artery disease patients; of these, eight (67%) had a short recovery and 4 (33%) had a long recovery. Late onset of ST segment depression occurred in eight patients with syndrome X; six (75%) had a short recovery and two (25%) had a long recovery.(ABSTRACT TRUNCATED AT 250 WORDS)
G Pupita; J C Kaski; A R Galassi; S Gavrielides; F Crea; A Maseri
Related Documents :
14720527 - Admission troponin t and measurement of st-segment resolution at 60 min improve early r...
6608367 - Assessment of aortocoronary bypass grafting using exercise st segment/heart rate relation.
11974667 - Significance of st-segment depression during supraventricular tachycardia. clues offere...
2662727 - Electrocardiographic manifestations of right ventricular infarction.
20516507 - Influence of age on long-term outcome after emergent percutaneous coronary intervention...
1763737 - Early angiographic and ct findings in patients with hemorrhagic infarction in the distr...
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  American heart journal     Volume:  120     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1990 Oct 
Date Detail:
Created Date:  1990-11-05     Completed Date:  1990-11-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  848-54     Citation Subset:  AIM; IM    
Cardiovascular Unit, Hammersmith Hospital, London, England.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Angina Pectoris / diagnosis,  physiopathology*
Coronary Disease / diagnosis,  physiopathology*
Exercise Test*
Middle Aged

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Comparison of coronary angiography and early oral dipyridamole thallium-201 scintigraphy in patients...
Next Document:  Prolongation of ventricular refractoriness by class Ia antiarrhythmic drugs in the prevention of ven...