Document Detail


Similar localization of immunoreactive glutamate and aspartate in the pineal organ and retina of various nonmammalian vertebrates.
MedLine Citation:
PMID:  8714767     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The localization of immunoreactive glutamate and aspartate was compared in the pineal organ and retina of various vertebrates (Raja clavata, Carassius auratus, Salvelinus alpinus, Triturus vulgaris, Triturus cristatus, Lacerta muralis, Lacerta agilis, Lacerta viridis, Columbia livia and white leghorn chicken) by postembedding immunoelectron microscopy. Immunoreaction of both excitatory amino acids was detected in the pinealocytes in a localization similar to that of retinal photoreceptors. The reaction was intense in the axonal processes of pinealocytes as well as retinal rods and cones, further in their terminals on secondary pineal and retinal neurons. Subsequent immunoreaction on the same section showed a colocalization of glutamate and aspartate. The accumulation of these amino acids in the presynaptic part of pinealocytes suggests that they act as synaptic mediators in the neural efferentation of the pineal organ. In reptiles and birds where the hormonal efferentation of the pineal is well developed, glutamate and aspartate was also found to be accumulated in neuroendocrine terminals of pinealocytes. Therefore, glutamate and aspartate may have a role in both the hormonal and neural efferentation of the pineal organ.
Authors:
B Vigh; K Debreceni; M J Manzano e Silva
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta biologica Hungarica     Volume:  46     ISSN:  0236-5383     ISO Abbreviation:  Acta. Biol. Hung.     Publication Date:  1995  
Date Detail:
Created Date:  1996-10-02     Completed Date:  1996-10-02     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8404358     Medline TA:  Acta Biol Hung     Country:  HUNGARY    
Other Details:
Languages:  eng     Pagination:  99-106     Citation Subset:  IM    
Affiliation:
Photoneuroendocrine Laboratory, Second Department of Anatomy, Histology and Embryology, Budapest, Hungary.
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MeSH Terms
Descriptor/Qualifier:
Amphibians
Animals
Aspartic Acid / metabolism*
Birds
Fishes
Glutamic Acid / metabolism*
Immunohistochemistry
Microscopy, Immunoelectron
Pineal Gland / metabolism*,  ultrastructure
Reptiles
Retina / metabolism*,  ultrastructure
Chemical
Reg. No./Substance:
56-84-8/Aspartic Acid; 56-86-0/Glutamic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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