Document Detail

Similar effects of foods high in protein, carbohydrate and fat on subsequent spontaneous food intake in healthy individuals.
MedLine Citation:
PMID:  12781159     Owner:  NLM     Status:  MEDLINE    
Pre-loads high in protein, as compared to carbohydrate and fat, produce greater satiety and reduce food intake after a fixed time interval. This study investigated the effect of macronutrient composition on spontaneous eating behaviour. On four separate occasions, 16 fasted, healthy, non-obese men, blinded to the true purpose of the study, consumed iso-energetic ( approximately 3MJ) yoghurt-based pre-loads of equivalent weight ( approximately 0.5 kg), high in fat (40%) [HF], carbohydrate (60%) [HC] or protein (29%) [HP], and no pre-load in a randomized, single-blind fashion. Subjects ate at will from a selection of food items for the remainder of the day (7 h) with the time of food requests (h) and energy content (kJ) and macronutrient distribution (%) of food eaten recorded. The three pre-loads delayed the first spontaneous request for food by 1.5-1.8 h relative to no pre-load. Total spontaneous food intake was suppressed 29% [HP], 20% [HF] and 17% [HC] by the pre-loads. Neither the amount of food eaten per spontaneous eating episode, nor the spontaneous eating frequency differed statistically following ingestion of the different pre-loads or no pre-load. In this study, in subjects who were free to choose when as well as how much they ate, a high-protein pre-load exerted similar effects on satiety as did iso-energetic high-fat and high-carbohydrate pre-loads.
Rosalie Vozzo; Gary Wittert; Carmel Cocchiaro; Wen Chien Tan; Jane Mudge; Rob Fraser; Ian Chapman
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Appetite     Volume:  40     ISSN:  0195-6663     ISO Abbreviation:  Appetite     Publication Date:  2003 Apr 
Date Detail:
Created Date:  2003-06-03     Completed Date:  2003-09-09     Revised Date:  2006-09-18    
Medline Journal Info:
Nlm Unique ID:  8006808     Medline TA:  Appetite     Country:  England    
Other Details:
Languages:  eng     Pagination:  101-7     Citation Subset:  IM    
Department of Medicine, Royal Adelaide Hospital, North Terrace, 5000, Adelaide, SA, Australia.
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MeSH Terms
Appetite / physiology*
Dietary Carbohydrates / pharmacology*
Dietary Fats / pharmacology*
Dietary Proteins / pharmacology*
Feeding Behavior*
Nutritive Value
Reg. No./Substance:
0/Dietary Carbohydrates; 0/Dietary Fats; 0/Dietary Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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