Document Detail


Similar effect of therapeutic ultrasound and antibiotics for acute bacterial rhinosinusitis: a randomised trial.
MedLine Citation:
PMID:  20500134     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
QUESTION: Is there any difference between the effect of therapeutic ultrasound and antibiotics (amoxicillin) on pain and congestion for acute bacterial rhinosinusitis in the short-term? Is there any difference in patient satisfaction, preferred future intervention, side-effects and relapses in the long-term?
DESIGN: A randomised trial with concealed allocation and intention-to-treat analysis.
PARTICIPANTS: 48 patients (6 dropouts) with clinically diagnosed acute bacterial rhinosinusitis in primary care.
INTERVENTION: The experimental group received 4 consecutive days of ultrasound and the control group received a 10-day course of antibiotics.
OUTCOME MEASURES: Pain and congestion around the nose and in the forehead and teeth were measured on a 0-10 numeric rating scale at baseline, Day 4, and Day 21. Satisfaction, preferred future intervention, side-effects, and relapses were measured one year later.
RESULTS: By Day 4, pain around the nose had decreased by 1.5 points out of 10 (95% CI 0.6 to 2.5) more in the experimental group than the control group. There were no other differences in decrease in pain and congestion between the groups at Day 4 or 21. At one year follow-up, the experimental group were more likely to prefer ultrasound than the control group were to prefer antibiotics to manage a future episode (RR 2.75, 95% CI 1.19 to 7.91). There were no other differences between the groups in terms of satisfaction with intervention, number of side-effects, or number of relapses.
CONCLUSION: The results of this study suggest that therapeutic ultrasound is a viable alternative to antibiotics in the management of acute bacterial rhinosinusitis.
TRIAL REGISTRATION: NCT00934830.
Authors:
Eli Høsøien; Anne B Lund; Ottar Vasseljen
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of physiotherapy     Volume:  56     ISSN:  1836-9553     ISO Abbreviation:  J Physiother     Publication Date:  2010  
Date Detail:
Created Date:  2010-05-26     Completed Date:  2010-08-13     Revised Date:  2014-07-30    
Medline Journal Info:
Nlm Unique ID:  101528691     Medline TA:  J Physiother     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  29-32     Citation Subset:  IM    
Data Bank Information
Bank Name/Acc. No.:
ClinicalTrials.gov/NCT00934830
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Adult
Amoxicillin / therapeutic use*
Anti-Bacterial Agents / therapeutic use*
Combined Modality Therapy
Female
Humans
Male
Middle Aged
Nasal Obstruction
Norway
Pain Measurement
Primary Health Care
Rhinitis / drug therapy,  microbiology,  therapy*
Sinusitis / drug therapy,  microbiology,  therapy*
Treatment Outcome
Ultrasonic Therapy / methods*
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 804826J2HU/Amoxicillin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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