Document Detail

Silver-binding nucleolar organizer regions (AgNORs) in bronchial tumors.
MedLine Citation:
PMID:  8617383     Owner:  NLM     Status:  MEDLINE    
Various AgNOR parameters were measured using the computer-aided image analysis in the normal bronchial epithelium (n = 13), in squamous cell carcinoma (n = 25) and in small-cell carcinoma (n = 11). The number and area of AgNOR dots were the highest in squamous cell carcinoma. In small cell carcinoma and in the normal epithelium the values were significantly lower. The number of AgNOR separate locations was higher in tumors in general. The size of single AgNOR dots showed differences between squamous cell carcinoma and small-cell carcinoma. Ratio of AgNOR dot area to nuclear area was similar in various pathological lesions and normal epithelium. There was a positive correlation ( < or = 0.0001) between the number and area of dots, the number of AgNOR separate locations, the area of single AgNOR dots on one hand and nuclear area on the other.
M Zaczek; Z Chłap; W Szot; K Gil; A Hajduk
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Folia histochemica et cytobiologica / Polish Academy of Sciences, Polish Histochemical and Cytochemical Society     Volume:  33     ISSN:  0239-8508     ISO Abbreviation:  Folia Histochem. Cytobiol.     Publication Date:  1995  
Date Detail:
Created Date:  1996-06-07     Completed Date:  1996-06-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8502651     Medline TA:  Folia Histochem Cytobiol     Country:  POLAND    
Other Details:
Languages:  eng     Pagination:  83-8     Citation Subset:  IM    
Department of Pathophysiology, Medical School of the Jagiellonian University, Kraków, Poland.
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MeSH Terms
Aged, 80 and over
Bronchial Neoplasms / diagnosis*,  pathology
Carcinoma, Small Cell / diagnosis,  pathology
Carcinoma, Squamous Cell / diagnosis*,  pathology
Cell Nucleus / ultrastructure
Diagnosis, Differential
Epithelial Cells
Lung / cytology
Middle Aged
Nucleolus Organizer Region* / pathology,  ultrastructure
Silver Staining*

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