Document Detail

Silver acetate mouth spray as an aid in smoking cessation: results of a double-blind trial.
MedLine Citation:
PMID:  8352038     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: We studied the use of an aversive technique to improve the outcome of smoking-cessation efforts. We hypothesized that a silver acetate mouth spray, which produces a strong aversive taste when cigarettes are smoked, would increase the quit rate among smokers. METHODS: Our study was a double-blind, placebo-controlled trial that was carried out in a private family practice office in an urban area. We studied 42 smokers, who were recruited by advertisement and who were motivated to quit by self-report. They were randomly assigned active spray or placebo spray; all were given a written list of behavioral suggestions. The spray was to be used every 2 hours for 3 weeks during which time the subjects were to keep diaries of cigarette smoking and spray use. Biochemical measures (salivary thiocyanate and cotinine) were recorded at entry, at 3 weeks, and at 3 months. RESULTS: Thirty smokers completed the study. No differences were found between the two groups in quit rate or number of cigarettes smoked. CONCLUSIONS: Silver acetate aversive spray did not increase quit rate among motivated smokers.
R Morrow; P Nepps; M McIntosh
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of the American Board of Family Practice / American Board of Family Practice     Volume:  6     ISSN:  0893-8652     ISO Abbreviation:  J Am Board Fam Pract     Publication Date:    1993 Jul-Aug
Date Detail:
Created Date:  1993-09-15     Completed Date:  1993-09-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8807505     Medline TA:  J Am Board Fam Pract     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  353-7     Citation Subset:  IM    
Department of Family Medicine, St. Joseph's Medical Center, Yonkers, NY.
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MeSH Terms
Acetic Acid
Acetic Acids / administration & dosage*
Aversive Therapy / methods*
Double-Blind Method
Family Practice
Middle Aged
Pilot Projects
Smoking Cessation / methods*,  psychology
Reg. No./Substance:
0/Acetic Acids; 0/Aerosols; 64-19-7/Acetic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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