| Silica nanoparticles as a delivery system for nucleic acid-based reagents. | |
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MedLine Citation:
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PMID: 20740060 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The transport of nucleic acid-based reagents is predicated upon developing structurally stable delivery systems that can preferentially bind and protect DNA and RNA, and release their cargo upon reaching their designated sites. Recent advancements in tailoring the size, shape, and external surface functionalization of silica materials have led to increased biocompatibility and efficiency of delivery. In this Feature Article, we highlight recent research progress in the use of silica nanoparticles as a delivery vehicle for nucleic acid-based reagents. |
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Authors:
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Christopher Hom; Jie Lu; Fuyuhiko Tamanoi |
Publication Detail:
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Type: JOURNAL ARTICLE |
Journal Detail:
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Title: Journal of materials chemistry Volume: 19 ISSN: 0959-9428 ISO Abbreviation: - Publication Date: 2009 Jan |
Date Detail:
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Created Date: 2010-11-5 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9889099 Medline TA: J Mater Chem Country: - |
Other Details:
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Languages: ENG Pagination: 6308-6316 Citation Subset: - |
Affiliation:
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Department of Microbiology, Immunology, and Molecular Genetics, California NanoSystems Institute, JCCC, University of California, 609 Charles E. Young Drive East, Los Angeles, CA, 90095, USA. fuyut@microbio.ucla.edu ; ; Tel: (+310) 206-7318. |
Export Citation:
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Descriptor/Qualifier:
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| Grant Support | |
ID/Acronym/Agency:
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R01 CA133697-02//NCI NIH HHS; R01 CA133697-02//NCI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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