Document Detail


Silent myocardial ischemia in patients with myocardial infarction: evaluation with positron emission computed tomography.
MedLine Citation:
PMID:  2621773     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To evaluate myocardial blood flow and glucose utilization, N-13 ammonia and F-18 deoxyglucose positron emission tomography were performed in 33 patients with myocardial infarction. The N-13 ammonia study was performed at rest and during supine exercise, and the F-18 deoxyglucose was done at rest after greater than or equal to 5 hours of fasting. Based on angina, exercise-induced hypoperfusion, and deoxyglucose uptake, 3 groups of patients were classified; 10 patients in group I (neither angina nor exercise induced hypoperfusion), 8 patients in group II (painless exercise-induced hypoperfusion) and 15 patients in group III (anginal patients with/without exercise-induced hypoperfusion). The F-18 deoxyglucose positron study demonstrated accumulation of deoxyglucose in 6 patients in group I, 7 in group II, and 14 in group III. Thus, our results indicated that a significant number of patients with antecedent myocardial infarction had exercise-induced hypoperfusion and/or altered glucose metabolism without accompanying anginal pain.
Authors:
H Kambara; T Fudo; T Hashimoto; M Hayashi; C Kawai; N Tamaki; K Yamashita; Y Yonekura; J Konishi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Japanese circulation journal     Volume:  53     ISSN:  0047-1828     ISO Abbreviation:  Jpn. Circ. J.     Publication Date:  1989 Nov 
Date Detail:
Created Date:  1990-03-23     Completed Date:  1990-03-23     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7806868     Medline TA:  Jpn Circ J     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  1437-43     Citation Subset:  IM    
Affiliation:
Kyoto University College of Medical Technology, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Ammonia / diagnostic use
Angina Pectoris / etiology,  physiopathology,  radionuclide imaging
Coronary Circulation
Coronary Disease / etiology*,  physiopathology,  radionuclide imaging
Deoxyglucose / analogs & derivatives,  diagnostic use,  pharmacokinetics
Exercise Test
Fluorine Radioisotopes / diagnostic use,  pharmacokinetics
Fluorodeoxyglucose F18
Glucose / metabolism
Heart / radionuclide imaging*
Humans
Middle Aged
Myocardial Infarction / complications*
Myocardium / metabolism
Nitrogen Radioisotopes / diagnostic use
Tomography, Emission-Computed
Chemical
Reg. No./Substance:
0/Fluorine Radioisotopes; 0/Nitrogen Radioisotopes; 154-17-6/Deoxyglucose; 50-99-7/Glucose; 63503-12-8/Fluorodeoxyglucose F18; 7664-41-7/Ammonia

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