Document Detail

Silent myocardial infarction in Wegener's granulomatosis.
MedLine Citation:
PMID:  8612034     Owner:  NLM     Status:  MEDLINE    
Histological cardiac abnormalities in Wegener's granulomatosis can frequently be demonstrated at post-mortem examination, but clinically significant cardiac involvement is rare. We describe a massive silent myocardial infarction leading to intractable heart failure and death in a young man with Wegener's granulomatosis, occurring at a time when other features of the disease were responding to aggressive immunosuppression.
T M Lawson; B D Williams
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  British journal of rheumatology     Volume:  35     ISSN:  0263-7103     ISO Abbreviation:  Br. J. Rheumatol.     Publication Date:  1996 Feb 
Date Detail:
Created Date:  1996-05-31     Completed Date:  1996-05-31     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8302415     Medline TA:  Br J Rheumatol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  188-91     Citation Subset:  AIM; IM    
Department of Rheumatology, University Hospital of Wales, Cardiff.
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MeSH Terms
Cyclophosphamide / therapeutic use
Fatal Outcome
Immunosuppressive Agents / therapeutic use
Methylprednisolone / therapeutic use
Myocardial Infarction / complications*,  mortality,  physiopathology
Prednisolone / therapeutic use
Wegener Granulomatosis / complications*,  drug therapy
Reg. No./Substance:
0/Immunosuppressive Agents; 50-18-0/Cyclophosphamide; 50-24-8/Prednisolone; 83-43-2/Methylprednisolone

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