| Silent cerebral infarction in chronic atrial fibrillation. | |
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MedLine Citation:
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PMID: 3686584 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Atrial fibrillation (AF) is associated with an increased risk of stroke. In AF patients with acute stroke, cerebral computed tomography (CT) often reveals old asymptomatic infarcts. To investigate the frequency of such lesions, 29 AF patients and 29 controls in sinus rhythm without history of cerebrovascular disease were CT scanned. Fourteen patients with AF (48%) had abnormal CT scans with areas of low density with sharp demarcation from surrounding tissue compared with 8 patients in sinus rhythm (28%) (p greater than 0.10). However, the number of abnormal areas with apparent tissue loss was significantly higher in the AF group (39 lesions) compared with the control group (16 lesions) (p = 0.033). The lesions were mainly located in the cortex with no significant difference in lesion size between AF patients and controls. The abnormal areas probably reflected small, clinically silent infarcts. We conclude that these lesions are present in AF patients without history of cerebrovascular events and occur more frequently than in controls without atrial fibrillation. |
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Authors:
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P Petersen; E B Madsen; B Brun; F Pedersen; C Gyldensted; G Boysen |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Stroke; a journal of cerebral circulation Volume: 18 ISSN: 0039-2499 ISO Abbreviation: Stroke Publication Date: 1987 Nov-Dec |
Date Detail:
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Created Date: 1988-01-20 Completed Date: 1988-01-20 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0235266 Medline TA: Stroke Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1098-100 Citation Subset: IM |
Affiliation:
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Department of Neurology, University Hospital, Copenhagen, Denmark. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Atrial Fibrillation / complications* Cerebral Infarction / etiology*, radiography Chronic Disease Female Humans Male Middle Aged Risk Factors Tomography, X-Ray Computed |
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