| Silent cardiac dysfunction and exercise intolerance in HIV+ men receiving combined antiretroviral therapies. | |
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MedLine Citation:
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PMID: 19005278 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Resting and exercise cardiac function, skeletal muscle oxygenation and whole-body aerobic exercise capacities were evaluated prospectively in cardiac symptom-free HIV men receiving antiretroviral therapies and in healthy controls matched for age, physical activity, smoking and body surface area. HIV patients showed resting cardiac dysfunction, altered cardiac responses to exercise and depressed exercise tolerance. Exercise stroke volume kinetics and muscle oxygenation were impaired in HIV patients, especially in those with resting diastolic dysfunction. |
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Authors:
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Gilles J Thöni; Iris Schuster; Guillaume Walther; Stéphane Nottin; Agnès Vinet; Franck Boccara; Jean-Marc Mauboussin; Isabelle Rouanet; Stéphane Edérhy; Michel Dauzat; Patick Messner-Pellenc; Philippe Obert |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: AIDS (London, England) Volume: 22 ISSN: 1473-5571 ISO Abbreviation: AIDS Publication Date: 2008 Nov |
Date Detail:
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Created Date: 2008-11-13 Completed Date: 2009-02-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8710219 Medline TA: AIDS Country: England |
Other Details:
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Languages: eng Pagination: 2537-40 Citation Subset: IM; X |
Affiliation:
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EA 4278, Faculty of Sciences, Avignon, France. gilles.thoni@univ-montp1.fr |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anaerobic Threshold / physiology Antiretroviral Therapy, Highly Active Electrocardiography Exercise / physiology* Exercise Test Exercise Tolerance / physiology HIV Infections / complications, drug therapy, physiopathology* Humans Male Middle Aged Muscle, Skeletal / metabolism Prospective Studies Stroke Volume / physiology Ventricular Dysfunction, Left / physiopathology, virology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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